GO Annotations Graph

• Symbol: Pfkl
• Name: phosphofructokinase, liver, B-type
• ID: MGI:97547

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003872	6-phosphofructokinase activity	ISO	J:164563
Molecular Function	GO:0003872	6-phosphofructokinase activity	ISO	J:155856
Molecular Function	GO:0003872	6-phosphofructokinase activity	ISO	J:164563
Molecular Function	GO:0003872	6-phosphofructokinase activity	IBA	J:265628
Molecular Function	GO:0003872	6-phosphofructokinase activity	IDA	J:223061
Molecular Function	GO:0003872	6-phosphofructokinase activity	IDA	J:18425
Molecular Function	GO:0003872	6-phosphofructokinase activity	IDA	J:18425
Molecular Function	GO:0003872	6-phosphofructokinase activity	IDA	J:18425
Molecular Function	GO:0003872	6-phosphofructokinase activity	IDA	J:42576
Molecular Function	GO:0016208	AMP binding	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IBA	J:265628
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0070061	fructose binding	ISO	J:164563
Molecular Function	GO:0070095	fructose-6-phosphate binding	ISO	J:155856
Molecular Function	GO:0070095	fructose-6-phosphate binding	ISO	J:164563
Molecular Function	GO:0070095	fructose-6-phosphate binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IBA	J:265628
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0048029	monosaccharide binding	ISO	J:155856
Molecular Function	GO:0048029	monosaccharide binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005945	6-phosphofructokinase complex	ISO	J:164563
Cellular Component	GO:0005945	6-phosphofructokinase complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:139710
Cellular Component	GO:0016020	membrane	IBA	J:265628
Biological Process	GO:0061621	canonical glycolysis	IBA	J:265628
Biological Process	GO:0005975	carbohydrate metabolic process	ISO	J:155856
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ISO	J:164563
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ISO	J:155856
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	IBA	J:265628
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	ISO	J:164563
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	ISO	J:155856
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	IBA	J:265628
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	IDA	J:18425
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	IDA	J:42576
Biological Process	GO:0006096	glycolytic process	ISO	J:164563
Biological Process	GO:0006096	glycolytic process	ISO	J:155856
Biological Process	GO:0061615	glycolytic process through fructose-6-phosphate	IDA	J:18425
Biological Process	GO:0061615	glycolytic process through fructose-6-phosphate	IMP	J:332287
Biological Process	GO:0061615	glycolytic process through fructose-6-phosphate	IMP	J:332287
Biological Process	GO:0061615	glycolytic process through fructose-6-phosphate	IDA	J:42576
Biological Process	GO:0061615	glycolytic process through fructose-6-phosphate	IDA	J:18425
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0046676	negative regulation of insulin secretion	IDA	J:42576
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0009749	response to glucose	ISO	J:164563
Biological Process	GO:0009749	response to glucose	IDA	J:42576