GO Annotations Graph

• Symbol: Pgk1
• Name: phosphoglycerate kinase 1
• ID: MGI:97555

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0043531	ADP binding	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IBA	J:265628
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004618	phosphoglycerate kinase activity	ISO	J:155856
Molecular Function	GO:0004618	phosphoglycerate kinase activity	ISO	J:164563
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IBA	J:265628
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:5427
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:5427
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:5427
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:5427
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:4489
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:5618
Molecular Function	GO:0004618	phosphoglycerate kinase activity	IDA	J:7062
Molecular Function	GO:0005515	protein binding	IPI	J:278187
Molecular Function	GO:0047134	protein-disulfide reductase (NAD(P)) activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:240546
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:319900
Cellular Component	GO:0005829	cytosol	IDA	J:320603
Cellular Component	GO:0005829	cytosol	IDA	J:320603
Cellular Component	GO:0005829	cytosol	IDA	J:320603
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Biological Process	GO:0061621	canonical glycolysis	IGI	J:317782
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0006094	gluconeogenesis	IBA	J:265628
Biological Process	GO:0006094	gluconeogenesis	IGI	J:152724
Biological Process	GO:0006094	gluconeogenesis	IGI	J:152724
Biological Process	GO:0006094	gluconeogenesis	IGI	J:152724
Biological Process	GO:0006096	glycolytic process	ISO	J:164563
Biological Process	GO:0006096	glycolytic process	IBA	J:265628
Biological Process	GO:0006096	glycolytic process	IDA	J:95517
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0031639	plasminogen activation	ISO	J:164563