GO Annotations Graph

• Symbol: Abcb4
• Name: ATP-binding cassette, sub-family B member 4
• ID: MGI:97569

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IEA	J:72245
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	ISO	J:164563
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0046581	intercellular canaliculus	IDA	J:77485
Cellular Component	GO:0016020	membrane	IDA	J:68661
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:32078
Cellular Component	GO:0005886	plasma membrane	TAS	J:15531
Biological Process	GO:0032782	bile acid secretion	IMP	J:15531
Biological Process	GO:1903413	cellular response to bile acid	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:0045332	phospholipid translocation	IBA	J:265628
Biological Process	GO:0032376	positive regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0061092	positive regulation of phospholipid translocation	ISO	J:164563
Biological Process	GO:2001140	positive regulation of phospholipid transport	ISO	J:164563
Biological Process	GO:1901557	response to fenofibrate	IDA	J:32078
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628