GO Annotations Graph

• Symbol: Abcb1a
• Name: ATP-binding cassette, sub-family B member 1A
• ID: MGI:97570

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IDA	J:74642
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IEA	J:72245
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	EXP	J:231283
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046943	carboxylic acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0099038	ceramide floppase activity	ISO	J:164563
Molecular Function	GO:0099038	ceramide floppase activity	IDA	J:235270
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015562	efflux transmembrane transporter activity	IMP	J:280384
Molecular Function	GO:0140328	floppase activity	IMP	J:235270
Molecular Function	GO:0140328	floppase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	IDA	J:235270
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	ISO	J:164563
Molecular Function	GO:0090555	phosphatidylethanolamine flippase activity	IDA	J:235270
Molecular Function	GO:0090555	phosphatidylethanolamine flippase activity	ISO	J:164563
Molecular Function	GO:0022857	transmembrane transporter activity	IMP	J:280384
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	IMP	J:280384
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:235270
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0046581	intercellular canaliculus	IDA	J:77485
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2161526
Biological Process	GO:1905039	carboxylic acid transmembrane transport	ISO	J:164563
Biological Process	GO:0099040	ceramide translocation	ISO	J:164563
Biological Process	GO:0099040	ceramide translocation	IDA	J:235270
Biological Process	GO:0099040	ceramide translocation	IBA	J:265628
Biological Process	GO:0140115	export across plasma membrane	IMP	J:280384
Biological Process	GO:0140115	export across plasma membrane	ISO	J:164563
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0045332	phospholipid translocation	IDA	J:235270
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:1901529	positive regulation of anion channel activity	ISO	J:164563
Biological Process	GO:2001225	regulation of chloride transport	ISO	J:164563
Biological Process	GO:0047484	regulation of response to osmotic stress	ISO	J:164563
Biological Process	GO:0072089	stem cell proliferation	ISO	J:164563
Biological Process	GO:0046865	terpenoid transport	IMP	J:280384
Biological Process	GO:0070633	transepithelial transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	ISO	J:164563
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	IDA	J:74642
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	IMP	J:280384
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	ISO	J:164563