GO Annotations Graph

• Symbol: Prkcg
• Name: protein kinase C, gamma
• ID: MGI:97597

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0004698	calcium-dependent protein kinase C activity	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:193126
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	ISO	J:199676
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0044305	calyx of Held	IDA	J:220910
Cellular Component	GO:0044305	calyx of Held	IDA	J:220910
Cellular Component	GO:0044305	calyx of Held	IMP	J:220910
Cellular Component	GO:0044305	calyx of Held	IDA	J:220910
Cellular Component	GO:0044305	calyx of Held	IDA	J:220910
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0005737	cytoplasm	IDA	J:127350
Cellular Component	GO:0005737	cytoplasm	IDA	J:87315
Cellular Component	GO:0005737	cytoplasm	IDA	J:63657
Cellular Component	GO:0005737	cytoplasm	IDA	J:63657
Cellular Component	GO:0005737	cytoplasm	IDA	J:71483
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:71483
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:87315
Cellular Component	GO:0005634	nucleus	IDA	J:63657
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:127350
Cellular Component	GO:0005886	plasma membrane	IDA	J:63657
Cellular Component	GO:0099524	postsynaptic cytosol	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:187362
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:220910
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:220910
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	IDA	J:175506
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:31211
Biological Process	GO:0007635	chemosensory behavior	IMP	J:79995
Biological Process	GO:0060384	innervation	IMP	J:31211
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0060291	long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	IMP	J:193126
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IMP	J:193126
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	ISO	J:164563
Biological Process	GO:0032425	positive regulation of mismatch repair	ISO	J:164563
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:220910
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:220910
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:220910
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:193126
Biological Process	GO:0050764	regulation of phagocytosis	IMP	J:88811
Biological Process	GO:0032095	regulation of response to food	IMP	J:193126
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:220910
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:220910
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:220910
Biological Process	GO:0043278	response to morphine	IMP	J:126193
Biological Process	GO:0048265	response to pain	IMP	J:43458
Biological Process	GO:1990911	response to psychosocial stress	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000