GO Annotations Graph

• Symbol: Prkcd
• Name: protein kinase C, delta
• ID: MGI:97598

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0004698	calcium-dependent protein kinase C activity	IEA	J:72245
Molecular Function	GO:0004699	calcium-independent protein kinase C activity	ISO	J:155856
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0043560	insulin receptor substrate binding	IPI	J:145810
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:222149
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0004697	protein kinase C activity	IDA	J:189256
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:155856
Molecular Function	GO:0004697	protein kinase C activity	ISO	J:164563
Molecular Function	GO:0106310	protein serine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:181290
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0070976	TIR domain binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:63657
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:63657
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0036019	endolysosome	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:149031
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	IDA	J:63657
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:63657
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0099524	postsynaptic cytosol	ISO	J:155856
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0042100	B cell proliferation	IMP	J:76135
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:1904385	cellular response to angiotensin	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0071447	cellular response to hydroperoxide	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:155856
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	ISO	J:164563
Biological Process	GO:0032963	collagen metabolic process	ISO	J:155856
Biological Process	GO:0070779	D-aspartate import across plasma membrane	ISO	J:155856
Biological Process	GO:0042742	defense response to bacterium	IMP	J:189256
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:76135
Biological Process	GO:0032613	interleukin-10 production	IMP	J:99289
Biological Process	GO:0032615	interleukin-12 production	IMP	J:99289
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:155856
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0030837	negative regulation of actin filament polymerization	IMP	J:140440
Biological Process	GO:0051490	negative regulation of filopodium assembly	IMP	J:140440
Biological Process	GO:0034351	negative regulation of glial cell apoptotic process	ISO	J:164563
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IMP	J:145810
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	IMP	J:148072
Biological Process	GO:0090331	negative regulation of platelet aggregation	IMP	J:140440
Biological Process	GO:0042119	neutrophil activation	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IDA	J:99082
Biological Process	GO:2000304	positive regulation of ceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0032079	positive regulation of endodeoxyribonuclease activity	ISO	J:164563
Biological Process	GO:0046326	positive regulation of glucose import	ISO	J:155856
Biological Process	GO:2000753	positive regulation of glucosylceramide catabolic process	ISO	J:164563
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:155856
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:155856
Biological Process	GO:1900163	positive regulation of phospholipid scramblase activity	ISO	J:164563
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	ISO	J:164563
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:2000755	positive regulation of sphingomyelin catabolic process	ISO	J:164563
Biological Process	GO:0032930	positive regulation of superoxide anion generation	ISO	J:164563
Biological Process	GO:0043687	post-translational protein modification	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:2000303	regulation of ceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0042325	regulation of phosphorylation	ISO	J:155856
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0023021	termination of signal transduction	ISO	J:164563