GO Annotations Graph

• Symbol: Plp1
• Name: proteolipid protein (myelin) 1
• ID: MGI:97623

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:93976
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0019911	structural constituent of myelin sheath	ISO	J:155856
Molecular Function	GO:0019911	structural constituent of myelin sheath	IBA	J:265628
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	IBA	J:265628
Cellular Component	GO:0043209	myelin sheath	IDA	J:167272
Cellular Component	GO:0043209	myelin sheath	IDA	J:10575
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0098990	AMPA selective glutamate receptor signaling pathway	ISO	J:155856
Biological Process	GO:0014002	astrocyte development	IGI	J:201143
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0061564	axon development	IGI	J:201143
Biological Process	GO:0008366	axon ensheathment	IMP	J:13141
Biological Process	GO:0022010	central nervous system myelination	IBA	J:265628
Biological Process	GO:0022010	central nervous system myelination	IMP	J:10575
Biological Process	GO:0010001	glial cell differentiation	ISO	J:155856
Biological Process	GO:0006954	inflammatory response	IGI	J:201143
Biological Process	GO:0042759	long-chain fatty acid biosynthetic process	IMP	J:106960
Biological Process	GO:0042552	myelination	ISO	J:155856
Biological Process	GO:0042552	myelination	IGI	J:201143
Biological Process	GO:0042552	myelination	TAS	J:77770
Biological Process	GO:0042552	myelination	IMP	J:849
Biological Process	GO:0042552	myelination	IMP	J:242069
Biological Process	GO:0042552	myelination	IMP	J:106960
Biological Process	GO:1904427	positive regulation of calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:145263
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:849