GO Annotations Graph

• Symbol: Prkar1b
• Name: protein kinase, cAMP dependent regulatory, type I beta
• ID: MGI:97759

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030552	cAMP binding	ISO	J:155856
Molecular Function	GO:0004862	cAMP-dependent protein kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISO	J:155856
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISO	J:164563
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISS	J:39500
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISS	J:19854
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	ISO	J:164563
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	ISO	J:155856
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	IDA	J:177007
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:177007
Cellular Component	GO:0005737	cytoplasm	TAS	J:39705
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:157360
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:157360
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:28735
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:28735
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:206458
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:30405
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:30405
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005771	multivesicular body	IDA	J:177007
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	IDA	J:157360
Cellular Component	GO:0098794	postsynapse	IMP	J:157360
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:38837
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:38837
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:28735
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:28735
Cellular Component	GO:0045202	synapse	EXP	J:206458
Cellular Component	GO:0045202	synapse	IDA	J:206458
Biological Process	GO:0009887	animal organ morphogenesis	TAS	J:25553
Biological Process	GO:0007611	learning or memory	IMP	J:28735
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:38837
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:38837
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:28735
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:28735
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:28735
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:28735
Biological Process	GO:2000480	negative regulation of cAMP-dependent protein kinase activity	ISO	J:164563
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:1903367	positive regulation of fear response	ISO	J:155856
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:1904058	positive regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	TAS	J:25553
Biological Process	GO:0045859	regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0001932	regulation of protein phosphorylation	IEA	J:72247
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IMP	J:30405
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	IDA	J:30405