GO Annotations Graph

• Symbol: Prkar2b
• Name: protein kinase, cAMP dependent regulatory, type II beta
• ID: MGI:97760

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030552	cAMP binding	ISO	J:155856
Molecular Function	GO:0004862	cAMP-dependent protein kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISO	J:155856
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	ISO	J:164563
Molecular Function	GO:0008603	cAMP-dependent protein kinase regulator activity	IDA	J:25553
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:245376
Molecular Function	GO:0005515	protein binding	IPI	J:124778
Molecular Function	GO:0005515	protein binding	IPI	J:245390
Molecular Function	GO:0005515	protein binding	IPI	J:245387
Molecular Function	GO:0005515	protein binding	IPI	J:172115
Molecular Function	GO:0005515	protein binding	IPI	J:206832
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:206832
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	ISO	J:155856
Cellular Component	GO:0005952	cAMP-dependent protein kinase complex	IDA	J:177007
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0097546	ciliary base	IDA	J:181006
Cellular Component	GO:0097546	ciliary base	IDA	J:181006
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:177007
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	IDA	J:206832
Cellular Component	GO:0043197	dendritic spine	IDA	J:206832
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:157360
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:157360
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:97151
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:97151
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	IDA	J:157360
Cellular Component	GO:0098794	postsynapse	IMP	J:157360
Cellular Component	GO:0098794	postsynapse	IDA	J:206832
Cellular Component	GO:0098794	postsynapse	IDA	J:206832
Cellular Component	GO:0098794	postsynapse	IDA	J:206832
Biological Process	GO:0006631	fatty acid metabolic process	IMP	J:34751
Biological Process	GO:0007612	learning	IMP	J:47453
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:97151
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:97151
Biological Process	GO:2000480	negative regulation of cAMP-dependent protein kinase activity	ISO	J:164563
Biological Process	GO:0045859	regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0001932	regulation of protein phosphorylation	IEA	J:72247