GO Annotations Graph

• Symbol: Prps1
• Name: phosphoribosyl pyrophosphate synthetase 1
• ID: MGI:97775

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0016208	AMP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IBA	J:265628
Molecular Function	GO:0030246	carbohydrate binding	ISO	J:155856
Molecular Function	GO:0019003	GDP binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	ISO	J:155856
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	ISO	J:164563
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	IBA	J:265628
Molecular Function	GO:0004749	ribose phosphate diphosphokinase activity	IDA	J:224459
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:267013
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0002189	ribose phosphate diphosphokinase complex	ISO	J:155856
Cellular Component	GO:0002189	ribose phosphate diphosphokinase complex	IBA	J:265628
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	IBA	J:265628
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	IDA	J:224459
Biological Process	GO:0044249	cellular biosynthetic process	IEA	J:72247
Biological Process	GO:0046101	hypoxanthine biosynthetic process	ISO	J:164563
Biological Process	GO:0007399	nervous system development	ISO	J:164563
Biological Process	GO:0009165	nucleotide biosynthetic process	IEA	J:72247
Biological Process	GO:0009165	nucleotide biosynthetic process	IEA	J:60000
Biological Process	GO:0006098	pentose-phosphate shunt	IMP	J:214383
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0006144	purine nucleobase metabolic process	ISO	J:164563
Biological Process	GO:0006164	purine nucleotide biosynthetic process	ISO	J:164563
Biological Process	GO:0006164	purine nucleotide biosynthetic process	IBA	J:265628
Biological Process	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEA	J:72247
Biological Process	GO:0034418	urate biosynthetic process	ISO	J:164563