GO Annotations Graph

• Symbol: Ptbp1
• Name: polypyrimidine tract binding protein 1
• ID: MGI:97791

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:155856
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0036002	pre-mRNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:100326
Molecular Function	GO:0001069	regulatory region RNA binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IPI	J:224225
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0044306	neuron projection terminus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IPI	J:224225
Cellular Component	GO:0005634	nucleus	IDA	J:64959
Biological Process	GO:0070935	3'-UTR-mediated mRNA stabilization	ISO	J:155856
Biological Process	GO:0010467	gene expression	IGI	J:224225
Biological Process	GO:0010467	gene expression	IMP	J:224225
Biological Process	GO:0075522	IRES-dependent viral translational initiation	ISO	J:164563
Biological Process	GO:0006397	mRNA processing	ISO	J:155856
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	IDA	J:268025
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	IMP	J:204486
Biological Process	GO:0051148	negative regulation of muscle cell differentiation	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	IDA	J:268025
Biological Process	GO:0033119	negative regulation of RNA splicing	ISO	J:164563
Biological Process	GO:0022008	neurogenesis	IMP	J:224225
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	ISO	J:155856
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	ISO	J:164563
Biological Process	GO:1904411	positive regulation of secretory granule organization	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:0045727	positive regulation of translation	ISO	J:155856
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0045595	regulation of cell differentiation	IBA	J:265628
Biological Process	GO:0043484	regulation of RNA splicing	IBA	J:265628
Biological Process	GO:0008380	RNA splicing	IEA	J:60000