GO Annotations Graph

• Symbol: Ptger2
• Name: prostaglandin E receptor 2 (subtype EP2)
• ID: MGI:97794

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004957	prostaglandin E receptor activity	ISO	J:155856
Molecular Function	GO:0004957	prostaglandin E receptor activity	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:183216
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	IDA	J:183216
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0072639	interleukin-33 production	IMP	J:301363
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:1904346	positive regulation of gastric mucosal blood circulation	ISO	J:155856
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:71543
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:98317
Biological Process	GO:0009624	response to nematode	IMP	J:301363
Biological Process	GO:0032570	response to progesterone	IDA	J:219111
Biological Process	GO:0007165	signal transduction	IEA	J:60000