GO Annotations Graph

• Symbol: Ptgs1
• Name: prostaglandin-endoperoxide synthase 1
• ID: MGI:97797

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IBA	J:265628
Molecular Function	GO:0004601	peroxidase activity	IEA	J:60000
Molecular Function	GO:0004601	peroxidase activity	IEA	J:72247
Molecular Function	GO:0004666	prostaglandin-endoperoxide synthase activity	ISO	J:164563
Molecular Function	GO:0004666	prostaglandin-endoperoxide synthase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005737	cytoplasm	IDA	J:77512
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005737	cytoplasm	ISO	J:79955
Cellular Component	GO:0005737	cytoplasm	IDA	J:79955
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:79955
Biological Process	GO:0019371	cyclooxygenase pathway	ISO	J:164563
Biological Process	GO:0019371	cyclooxygenase pathway	IBA	J:265628
Biological Process	GO:0006633	fatty acid biosynthetic process	IEA	J:60000
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:72247
Biological Process	GO:0030216	keratinocyte differentiation	NAS	J:77156
Biological Process	GO:0007612	learning	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0035633	maintenance of blood-brain barrier	ISO	J:155856
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0032811	negative regulation of epinephrine secretion	ISO	J:155856
Biological Process	GO:0010700	negative regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	ISO	J:155856
Biological Process	GO:0045907	positive regulation of vasoconstriction	ISO	J:155856
Biological Process	GO:0001516	prostaglandin biosynthetic process	ISO	J:155856
Biological Process	GO:0001516	prostaglandin biosynthetic process	IMP	J:77475
Biological Process	GO:0006693	prostaglandin metabolic process	IMP	J:64401
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:77475
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:64401
Biological Process	GO:0006979	response to oxidative stress	IEA	J:72247
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856