GO Annotations Graph

• Symbol: Nectin2
• Name: nectin cell adhesion molecule 2
• ID: MGI:97822

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	IPI	J:143697
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0050839	cell adhesion molecule binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:245343
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:243463
Molecular Function	GO:0005515	protein binding	IPI	J:84887
Molecular Function	GO:0005515	protein binding	IPI	J:97476
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:85426
Cellular Component	GO:0043296	apical junction complex	IBA	J:265628
Cellular Component	GO:0043296	apical junction complex	IDA	J:213985
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0044291	cell-cell contact zone	IDA	J:195272
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:101707
Cellular Component	GO:0005911	cell-cell junction	IDA	J:96238
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:85426
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005915	zonula adherens	IDA	J:143697
Biological Process	GO:0001675	acrosome assembly	IBA	J:265628
Biological Process	GO:0001675	acrosome assembly	IMP	J:61334
Biological Process	GO:0044406	adhesion of symbiont to host	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0032990	cell part morphogenesis	IMP	J:61334
Biological Process	GO:0044782	cilium organization	IMP	J:61334
Biological Process	GO:0046814	coreceptor-mediated virion attachment to host cell	ISO	J:164563
Biological Process	GO:0046814	coreceptor-mediated virion attachment to host cell	IBA	J:265628
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0007010	cytoskeleton organization	IMP	J:61334
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:61334
Biological Process	GO:0051654	establishment of mitochondrion localization	IBA	J:265628
Biological Process	GO:0051654	establishment of mitochondrion localization	IMP	J:61334
Biological Process	GO:0009566	fertilization	IMP	J:61334
Biological Process	GO:0019064	fusion of virus membrane with host plasma membrane	ISO	J:164563
Biological Process	GO:0019064	fusion of virus membrane with host plasma membrane	IBA	J:265628
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IDA	J:85426
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IBA	J:265628
Biological Process	GO:0002891	positive regulation of immunoglobulin mediated immune response	ISO	J:164563
Biological Process	GO:0002891	positive regulation of immunoglobulin mediated immune response	IBA	J:265628
Biological Process	GO:0033005	positive regulation of mast cell activation	ISO	J:164563
Biological Process	GO:0033005	positive regulation of mast cell activation	IBA	J:265628
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	ISO	J:164563
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IBA	J:265628
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	IBA	J:265628
Biological Process	GO:0046596	regulation of viral entry into host cell	ISO	J:164563
Biological Process	GO:0046596	regulation of viral entry into host cell	IBA	J:265628
Biological Process	GO:0030382	sperm mitochondrion organization	IMP	J:61334
Biological Process	GO:0007286	spermatid development	IMP	J:61334
Biological Process	GO:0007289	spermatid nucleus differentiation	IMP	J:61334
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	IBA	J:265628
Biological Process	GO:0060370	susceptibility to T cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0060370	susceptibility to T cell mediated cytotoxicity	IBA	J:265628
Biological Process	GO:0019062	virion attachment to host cell	IEA	J:72247