GO Annotations Graph

• Symbol: Rac2
• Name: Rac family small GTPase 2
• ID: MGI:97846

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IDA	J:91862
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0019887	protein kinase regulator activity	IMP	J:111999
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:78781
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:78781
Cellular Component	GO:0016020	membrane	IDA	J:78781
Cellular Component	GO:0005635	nuclear envelope	IDA	J:78781
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:78781
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0045453	bone resorption	ISO	J:155856
Biological Process	GO:0008283	cell population proliferation	IMP	J:71331
Biological Process	GO:0008283	cell population proliferation	IGI	J:71331
Biological Process	GO:0030031	cell projection assembly	IDA	J:78781
Biological Process	GO:0006935	chemotaxis	IDA	J:78781
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IGI	J:168922
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IGI	J:168922
Biological Process	GO:0071593	lymphocyte aggregation	ISO	J:164563
Biological Process	GO:0070662	mast cell proliferation	IMP	J:71331
Biological Process	GO:0070662	mast cell proliferation	IGI	J:71331
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	IMP	J:151789
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0070668	positive regulation of mast cell proliferation	IGI	J:71331
Biological Process	GO:0070668	positive regulation of mast cell proliferation	IMP	J:71331
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IMP	J:151789
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	ISO	J:164563
Biological Process	GO:0010810	regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0060753	regulation of mast cell chemotaxis	IMP	J:111999
Biological Process	GO:0043304	regulation of mast cell degranulation	IMP	J:111999
Biological Process	GO:1902622	regulation of neutrophil migration	ISO	J:164563
Biological Process	GO:0060263	regulation of respiratory burst	ISO	J:164563
Biological Process	GO:0042129	regulation of T cell proliferation	IMP	J:119437
Biological Process	GO:0007264	small GTPase mediated signal transduction	IEA	J:72247