GO Annotations Graph

• Symbol: Rbp4
• Name: retinol binding protein 4, plasma
• ID: MGI:97879

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:210500
Molecular Function	GO:0005515	protein binding	IPI	J:210500
Molecular Function	GO:0005515	protein binding	IPI	J:210500
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0016918	retinal binding	IEA	J:60000
Molecular Function	GO:0005501	retinoid binding	IEA	J:72247
Molecular Function	GO:0019841	retinol binding	ISO	J:164563
Molecular Function	GO:0019841	retinol binding	ISO	J:155856
Molecular Function	GO:0019841	retinol binding	IBA	J:265628
Molecular Function	GO:0019841	retinol binding	IDA	J:113580
Molecular Function	GO:0034632	retinol transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:99988
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:82903
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	IMP	J:113580
Biological Process	GO:0009790	embryo development	IGI	J:132367
Biological Process	GO:0048562	embryonic organ morphogenesis	IMP	J:101506
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	IMP	J:57513
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:101506
Biological Process	GO:0001654	eye development	IMP	J:101506
Biological Process	GO:0001654	eye development	ISO	J:164563
Biological Process	GO:0048807	female genitalia morphogenesis	IMP	J:101506
Biological Process	GO:0006094	gluconeogenesis	IMP	J:99988
Biological Process	GO:0006094	gluconeogenesis	ISO	J:164563
Biological Process	GO:0042593	glucose homeostasis	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:101506
Biological Process	GO:0060347	heart trabecula formation	IMP	J:82903
Biological Process	GO:0030324	lung development	IMP	J:101506
Biological Process	GO:0030277	maintenance of gastrointestinal epithelium	ISO	J:164563
Biological Process	GO:0008584	male gonad development	IMP	J:108574
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	IMP	J:82903
Biological Process	GO:0002639	positive regulation of immunoglobulin production	IDA	J:136442
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:164563
Biological Process	GO:0032868	response to insulin	IMP	J:99988
Biological Process	GO:0032526	response to retinoic acid	ISO	J:164563
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:71839
Biological Process	GO:0042574	retinal metabolic process	IMP	J:71839
Biological Process	GO:0042572	retinol metabolic process	ISO	J:164563
Biological Process	GO:0042572	retinol metabolic process	IGI	J:132367
Biological Process	GO:0034633	retinol transport	ISO	J:155856
Biological Process	GO:0034633	retinol transport	IBA	J:265628
Biological Process	GO:0034633	retinol transport	IMP	J:108574
Biological Process	GO:0034633	retinol transport	IGI	J:210500
Biological Process	GO:0034633	retinol transport	IMP	J:94165
Biological Process	GO:0034633	retinol transport	IMP	J:71839
Biological Process	GO:0034633	retinol transport	IMP	J:132367
Biological Process	GO:0034633	retinol transport	IMP	J:113580
Biological Process	GO:0007283	spermatogenesis	IMP	J:108574
Biological Process	GO:0060157	urinary bladder development	IMP	J:101506
Biological Process	GO:0060065	uterus development	IMP	J:101506
Biological Process	GO:0060068	vagina development	IMP	J:101506
Biological Process	GO:0071939	vitamin A import into cell	IMP	J:113580