GO Annotations Graph

• Symbol: Rad51
• Name: RAD51 recombinase
• ID: MGI:97890

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:105544
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	IBA	J:265628
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	IEA	J:72247
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:209337
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0070182	DNA polymerase binding	ISO	J:164563
Molecular Function	GO:0000150	DNA strand exchange activity	ISO	J:164563
Molecular Function	GO:0000150	DNA strand exchange activity	IBA	J:265628
Molecular Function	GO:0000150	DNA strand exchange activity	IDA	J:330110
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:292036
Molecular Function	GO:0005515	protein binding	IPI	J:273173
Molecular Function	GO:0005515	protein binding	IPI	J:167542
Molecular Function	GO:0005515	protein binding	IPI	J:84892
Molecular Function	GO:0005515	protein binding	IPI	J:72374
Molecular Function	GO:0005515	protein binding	IPI	J:95301
Molecular Function	GO:0005515	protein binding	IPI	J:39764
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003697	single-stranded DNA binding	IDA	J:188798
Molecular Function	GO:0017116	single-stranded DNA helicase activity	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IDA	J:273173
Cellular Component	GO:0005694	chromosome	IDA	J:291221
Cellular Component	GO:0005694	chromosome	IDA	J:268520
Cellular Component	GO:0005694	chromosome	IDA	J:297328
Cellular Component	GO:0005694	chromosome	IDA	J:285969
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:228560
Cellular Component	GO:0000793	condensed chromosome	IDA	J:62204
Cellular Component	GO:0000793	condensed chromosome	IDA	J:78200
Cellular Component	GO:0000793	condensed chromosome	IDA	J:120745
Cellular Component	GO:0000793	condensed chromosome	IDA	J:85108
Cellular Component	GO:0000793	condensed chromosome	IDA	J:120745
Cellular Component	GO:0000793	condensed chromosome	IDA	J:82397
Cellular Component	GO:0000794	condensed nuclear chromosome	IBA	J:265628
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:135578
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:87802
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:182264
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:195265
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:215796
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:236226
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:227337
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:161203
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:213984
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:268784
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0000800	lateral element	IDA	J:140402
Cellular Component	GO:0000800	lateral element	IDA	J:176168
Cellular Component	GO:0000800	lateral element	ISO	J:113839
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:194119
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0000228	nuclear chromosome	ISO	J:164563
Cellular Component	GO:0000152	nuclear ubiquitin ligase complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912421
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912431
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912462
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:113675
Cellular Component	GO:0005634	nucleus	IDA	J:268784
Cellular Component	GO:0005634	nucleus	IDA	J:296112
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:209337
Cellular Component	GO:0005634	nucleus	IDA	J:188798
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0099182	presynaptic intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	IDA	J:291221
Cellular Component	GO:0035861	site of double-strand break	IDA	J:273173
Cellular Component	GO:0035861	site of double-strand break	ISO	J:206795
Cellular Component	GO:0000795	synaptonemal complex	TAS	J:113675
Biological Process	GO:0071312	cellular response to alkaloid	IMP	J:188798
Biological Process	GO:0071312	cellular response to alkaloid	IMP	J:188798
Biological Process	GO:0072757	cellular response to camptothecin	ISO	J:164563
Biological Process	GO:0072711	cellular response to hydroxyurea	IMP	J:188798
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:164563
Biological Process	GO:0070192	chromosome organization involved in meiotic cell cycle	IBA	J:265628
Biological Process	GO:0070192	chromosome organization involved in meiotic cell cycle	IMP	J:188798
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	TAS	J:113675
Biological Process	GO:0006259	DNA metabolic process	IEA	J:72247
Biological Process	GO:0000730	DNA recombinase assembly	ISO	J:164563
Biological Process	GO:0000730	DNA recombinase assembly	IBA	J:265628
Biological Process	GO:0006310	DNA recombination	IEA	J:60000
Biological Process	GO:0006281	DNA repair	TAS	J:159275
Biological Process	GO:0006281	DNA repair	TAS	J:113675
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	ISO	J:164563
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	IDA	J:330110
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IDA	J:330110
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IDA	J:95301
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IMP	J:94149
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:105544
Biological Process	GO:0035518	histone H2A monoubiquitination	NAS	J:320082
Biological Process	GO:0036297	interstrand cross-link repair	ISO	J:164563
Biological Process	GO:0007141	male meiosis I	IDA	J:330110
Biological Process	GO:0051321	meiotic cell cycle	IDA	J:62204
Biological Process	GO:0051321	meiotic cell cycle	IDA	J:78200
Biological Process	GO:0006312	mitotic recombination	IBA	J:265628
Biological Process	GO:1990426	mitotic recombination-dependent replication fork processing	IEA	J:72247
Biological Process	GO:0051106	positive regulation of DNA ligation	ISO	J:164563
Biological Process	GO:0051865	protein autoubiquitination	NAS	J:320082
Biological Process	GO:0007131	reciprocal meiotic recombination	TAS	J:113675
Biological Process	GO:0007131	reciprocal meiotic recombination	IBA	J:265628
Biological Process	GO:2000001	regulation of DNA damage checkpoint	NAS	J:320084
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:188798
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:188798
Biological Process	GO:0031297	replication fork processing	ISO	J:164563
Biological Process	GO:0031297	replication fork processing	IMP	J:188798
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	IMP	J:188798
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	IMP	J:188798
Biological Process	GO:0042148	strand invasion	IBA	J:265628
Biological Process	GO:0000722	telomere maintenance via recombination	IGI	J:228560
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IGI	J:228560
Biological Process	GO:0032200	telomere organization	IMP	J:188798