GO Annotations Graph

• Symbol: Ret
• Name: ret proto-oncogene
• ID: MGI:97902

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:180801
Molecular Function	GO:0005515	protein binding	IPI	J:251981
Molecular Function	GO:0005515	protein binding	IPI	J:45720
Molecular Function	GO:0005515	protein binding	IPI	J:90843
Molecular Function	GO:0005515	protein binding	IPI	J:94527
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IDA	J:251981
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	TAS	J:72723
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098797	plasma membrane protein complex	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0009653	anatomical structure morphogenesis	TAS	J:72723
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:164563
Biological Process	GO:0001838	embryonic epithelial tube formation	IGI	J:94527
Biological Process	GO:0048484	enteric nervous system development	IMP	J:49702
Biological Process	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IEA	J:72247
Biological Process	GO:0060384	innervation	ISO	J:155856
Biological Process	GO:0000165	MAPK cascade	IGI	J:94527
Biological Process	GO:0033619	membrane protein proteolysis	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IMP	J:89887
Biological Process	GO:0001755	neural crest cell migration	IMP	J:106244
Biological Process	GO:0007158	neuron cell-cell adhesion	ISO	J:164563
Biological Process	GO:0007158	neuron cell-cell adhesion	IDA	J:180538
Biological Process	GO:0030182	neuron differentiation	IMP	J:126484
Biological Process	GO:0042551	neuron maturation	IMP	J:92351
Biological Process	GO:0061146	Peyer's patch morphogenesis	IMP	J:120816
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0045793	positive regulation of cell size	IMP	J:126484
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:117753
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:202649
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:202649
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0072300	positive regulation of metanephric glomerulus development	IMP	J:117753
Biological Process	GO:0014042	positive regulation of neuron maturation	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	IMP	J:204100
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0050770	regulation of axonogenesis	IMP	J:126484
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0048265	response to pain	IMP	J:159107
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IGI	J:47662
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IGI	J:47662
Biological Process	GO:0035799	ureter maturation	IMP	J:171426
Biological Process	GO:0001657	ureteric bud development	IMP	J:78712