GO Annotations Graph

• Symbol: Rrm2
• Name: ribonucleotide reductase M2
• ID: MGI:98181

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008199	ferric iron binding	IDA	J:240311
Molecular Function	GO:0042802	identical protein binding	IMP	J:240730
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:240730
Molecular Function	GO:0005515	protein binding	IPI	J:116942
Molecular Function	GO:0005515	protein binding	IPI	J:116926
Molecular Function	GO:0005515	protein binding	IPI	J:82758
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:240311
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IDA	J:148731
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IBA	J:265628
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IDA	J:116942
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IDA	J:116926
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IMP	J:10107
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IDA	J:31881
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	ISO	J:164563
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	IDA	J:240311
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	IMP	J:240730
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	IDA	J:148731
Biological Process	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IDA	J:314099
Biological Process	GO:0009265	2'-deoxyribonucleotide biosynthetic process	ISO	J:164563
Biological Process	GO:0001824	blastocyst development	IMP	J:256712
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	IDA	J:148731
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	IBA	J:265628
Biological Process	GO:0009262	deoxyribonucleotide metabolic process	IDA	J:82758
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0051290	protein heterotetramerization	IPI	J:148731
Biological Process	GO:0009185	ribonucleoside diphosphate metabolic process	ISO	J:164563
Biological Process	GO:0009185	ribonucleoside diphosphate metabolic process	IDA	J:314099