Rxra GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Rxra
retinoid X receptor alpha
MGI:98214

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:264834
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:130306
Molecular Function	GO:0003677	DNA binding	IDA	J:96189
Molecular Function	GO:0003677	DNA binding	IDA	J:95384
Molecular Function	GO:0050692	DNA binding domain binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:23077
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:73065
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:23077
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:73065
Molecular Function	GO:0043167	ion binding	ISO	J:164563
Molecular Function	GO:0050693	LBD domain binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:154828
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:94471
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:2326
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:155856
Molecular Function	GO:0003707	nuclear steroid receptor activity	IEA	J:72247
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:164563
Molecular Function	GO:0042277	peptide binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:178274
Molecular Function	GO:0005515	protein binding	IPI	J:30618
Molecular Function	GO:0005515	protein binding	IPI	J:81892
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:48279
Molecular Function	GO:0005515	protein binding	IPI	J:114350
Molecular Function	GO:0005515	protein binding	IPI	J:178274
Molecular Function	GO:0005515	protein binding	IPI	J:156072
Molecular Function	GO:0005515	protein binding	IPI	J:236712
Molecular Function	GO:0005515	protein binding	IPI	J:236712
Molecular Function	GO:0005515	protein binding	IPI	J:56144
Molecular Function	GO:0005515	protein binding	IPI	J:105576
Molecular Function	GO:0005515	protein binding	IPI	J:141260
Molecular Function	GO:0005515	protein binding	IPI	J:114735
Molecular Function	GO:0005515	protein binding	IPI	J:125396
Molecular Function	GO:0005515	protein binding	IPI	J:114735
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:164563
Molecular Function	GO:0044323	retinoic acid-responsive element binding	ISO	J:164563
Molecular Function	GO:0044323	retinoic acid-responsive element binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94492
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IPI	J:96189
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	IDA	J:78038
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:0043565	sequence-specific DNA binding	IGI	J:22384
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154828
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:178274
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Molecular Function	GO:0070644	vitamin D response element binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-442515
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:130306
Cellular Component	GO:0005634	nucleus	IDA	J:56144
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:154828
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:314644
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	EXP	J:320338
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NAS	J:45674
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:314562
Cellular Component	GO:0005667	transcription regulator complex	EXP	J:320125
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0060978	angiogenesis involved in coronary vascular morphogenesis	TAS	J:169941
Biological Process	GO:0043010	camera-type eye development	IGI	J:42773
Biological Process	GO:0055007	cardiac muscle cell differentiation	TAS	J:169941
Biological Process	GO:0060038	cardiac muscle cell proliferation	TAS	J:169941
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:44836
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:44836
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:94471
Biological Process	GO:0007566	embryo implantation	IGI	J:52278
Biological Process	GO:0010467	gene expression	IMP	J:264834
Biological Process	GO:0007507	heart development	TAS	J:169941
Biological Process	GO:0007507	heart development	IMP	J:48085
Biological Process	GO:0003007	heart morphogenesis	TAS	J:169941
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IGI	J:52278
Biological Process	GO:0030522	intracellular receptor signaling pathway	IDA	J:94471
Biological Process	GO:0001893	maternal placenta development	IGI	J:52278
Biological Process	GO:0060485	mesenchyme development	TAS	J:169941
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:2326
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	NAS	J:45674
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:314644
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	TAS	J:169941
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:178114
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001890	placenta development	IMP	J:44230
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0030501	positive regulation of bone mineralization	NAS	J:319681
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAS	J:169941
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:25214
Biological Process	GO:0002157	positive regulation of thyroid hormone mediated signaling pathway	IDA	J:314644
Biological Process	GO:0002157	positive regulation of thyroid hormone mediated signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:314644
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:2326
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:320075
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154828
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:198125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:198125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:92973
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:22384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:105576
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:204716
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105576
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98265
Biological Process	GO:0045994	positive regulation of translational initiation by iron	IGI	J:204716
Biological Process	GO:0070564	positive regulation of vitamin D receptor signaling pathway	ISO	J:164563
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	IMP	J:78553
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:94471
Biological Process	GO:0031641	regulation of myelination	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:94471
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:23077
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:23077
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	ISO	J:164563
Biological Process	GO:0032526	response to retinoic acid	IBA	J:265628
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IBA	J:265628
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IMP	J:204716
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IDA	J:2326
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IMP	J:78553
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IGI	J:44836
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	IMP	J:44836
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IMP	J:44836
Biological Process	GO:0061032	visceral serous pericardium development	TAS	J:169941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24