GO Annotations Graph

• Symbol: Scn1b
• Name: sodium channel, voltage-gated, type I, beta
• ID: MGI:98247

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:93341
Molecular Function	GO:0005515	protein binding	IPI	J:93341
Molecular Function	GO:0005272	sodium channel activity	IEA	J:60000
Molecular Function	GO:0019871	sodium channel inhibitor activity	IMP	J:127606
Molecular Function	GO:0019871	sodium channel inhibitor activity	IBA	J:265628
Molecular Function	GO:0017080	sodium channel regulator activity	ISO	J:164563
Molecular Function	GO:0017080	sodium channel regulator activity	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0005248	voltage-gated sodium channel activity	ISO	J:164563
Molecular Function	GO:0005248	voltage-gated sodium channel activity	ISO	J:164563
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	ISO	J:164563
Molecular Function	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	IMP	J:127606
Molecular Function	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0014704	intercalated disc	IDA	J:93341
Cellular Component	GO:0014704	intercalated disc	IDA	J:161910
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0033268	node of Ranvier	ISO	J:155856
Cellular Component	GO:0033268	node of Ranvier	IDA	J:90136
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0034706	sodium channel complex	IPI	J:93341
Cellular Component	GO:0034706	sodium channel complex	IPI	J:93341
Cellular Component	GO:0034706	sodium channel complex	IPI	J:93341
Cellular Component	GO:0030315	T-tubule	IDA	J:161910
Cellular Component	GO:0030315	T-tubule	IDA	J:93341
Cellular Component	GO:0001518	voltage-gated sodium channel complex	ISO	J:164563
Cellular Component	GO:0001518	voltage-gated sodium channel complex	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IMP	J:133207
Biological Process	GO:0061337	cardiac conduction	IMP	J:127606
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	ISO	J:164563
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	IBA	J:265628
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0021966	corticospinal neuron axon guidance	IMP	J:133207
Biological Process	GO:0040011	locomotion	IMP	J:90136
Biological Process	GO:0051899	membrane depolarization	ISO	J:164563
Biological Process	GO:0086012	membrane depolarization during cardiac muscle cell action potential	IMP	J:127606
Biological Process	GO:0086047	membrane depolarization during Purkinje myocyte cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	IGI	J:133207
Biological Process	GO:0031175	neuron projection development	IGI	J:133207
Biological Process	GO:0031175	neuron projection development	IGI	J:133207
Biological Process	GO:0031175	neuron projection development	IGI	J:133207
Biological Process	GO:0019227	neuronal action potential propagation	IMP	J:90136
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:133207
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:133207
Biological Process	GO:0010765	positive regulation of sodium ion transport	ISO	J:164563
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	IBA	J:265628
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0002028	regulation of sodium ion transport	ISO	J:155856
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	IMP	J:127606
Biological Process	GO:1905150	regulation of voltage-gated sodium channel activity	ISO	J:155856
Biological Process	GO:0046684	response to pyrethroid	ISO	J:155856
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0035725	sodium ion transmembrane transport	IMP	J:127606
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0006814	sodium ion transport	IEA	J:72247