GO Annotations Graph

• Symbol: Msr1
• Name: macrophage scavenger receptor 1
• ID: MGI:98257

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	IGI	J:241487
Molecular Function	GO:0001540	amyloid-beta binding	IBA	J:265628
Molecular Function	GO:0038024	cargo receptor activity	IGI	J:183868
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IMP	J:80905
Molecular Function	GO:0030169	low-density lipoprotein particle binding	IBA	J:265628
Molecular Function	GO:0005044	scavenger receptor activity	IEA	J:72247
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0034362	low-density lipoprotein particle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IMP	J:241487
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2173779
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-3221949
Biological Process	GO:0097242	amyloid-beta clearance	IMP	J:241487
Biological Process	GO:0097242	amyloid-beta clearance	IGI	J:183868
Biological Process	GO:0097242	amyloid-beta clearance	IBA	J:265628
Biological Process	GO:0030301	cholesterol transport	IMP	J:80905
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:120283
Biological Process	GO:0042953	lipoprotein transport	IMP	J:120283
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:241487
Biological Process	GO:0006911	phagocytosis, engulfment	IGI	J:183868
Biological Process	GO:0034381	plasma lipoprotein particle clearance	IMP	J:80905
Biological Process	GO:0034381	plasma lipoprotein particle clearance	IBA	J:265628
Biological Process	GO:0010886	positive regulation of cholesterol storage	IMP	J:80905
Biological Process	GO:0010886	positive regulation of cholesterol storage	IBA	J:265628
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	IGI	J:80905
Biological Process	GO:0006898	receptor-mediated endocytosis	IGI	J:183868