GO Annotations Graph

• Symbol: Sos2
• Name: SOS Ras/Rho guanine nucleotide exchange factor 2
• ID: MGI:98355

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:88364
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:88364
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IMP	J:100216
Molecular Function	GO:0005515	protein binding	IPI	J:114724
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:175120
Molecular Function	GO:0005515	protein binding	IPI	J:206901
Molecular Function	GO:0046982	protein heterodimerization activity	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0001782	B cell homeostasis	IGI	J:206090
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:326913
Biological Process	GO:0002260	lymphocyte homeostasis	IGI	J:206090
Biological Process	GO:0043547	positive regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0051057	positive regulation of small GTPase mediated signal transduction	ISO	J:155856
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:2000973	regulation of pro-B cell differentiation	IGI	J:206090
Biological Process	GO:0033081	regulation of T cell differentiation in thymus	IGI	J:206090
Biological Process	GO:0042129	regulation of T cell proliferation	IGI	J:206090
Biological Process	GO:0007264	small GTPase mediated signal transduction	IMP	J:100216