GO Annotations Graph

• Symbol: Sox6
• Name: SRY (sex determining region Y)-box 6
• ID: MGI:98368

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:173070
Molecular Function	GO:0003677	DNA binding	IDA	J:81702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:81702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:116148
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:50394
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	IDA	J:231103
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP	J:115753
Molecular Function	GO:0005515	protein binding	IPI	J:326902
Molecular Function	GO:0005515	protein binding	IPI	J:50394
Molecular Function	GO:0005515	protein binding	IPI	J:86174
Molecular Function	GO:0005515	protein binding	IPI	J:64789
Molecular Function	GO:0005515	protein binding	IPI	J:116148
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IMP	J:115753
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:241609
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:115753
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:116148
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:50394
Cellular Component	GO:0005634	nucleus	IDA	J:178379
Cellular Component	GO:0005634	nucleus	IC	J:81702
Cellular Component	GO:0005667	transcription regulator complex	IC	J:86174
Biological Process	GO:0048708	astrocyte differentiation	ISO	J:155856
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0055007	cardiac muscle cell differentiation	IDA	J:86174
Biological Process	GO:0055007	cardiac muscle cell differentiation	IDA	J:86174
Biological Process	GO:0001502	cartilage condensation	IMP	J:88817
Biological Process	GO:0001502	cartilage condensation	IMP	J:80666
Biological Process	GO:0051216	cartilage development	IMP	J:233055
Biological Process	GO:0051216	cartilage development	IDA	J:287044
Biological Process	GO:0051216	cartilage development	IGI	J:95359
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0045165	cell fate commitment	IGI	J:95359
Biological Process	GO:0000902	cell morphogenesis	IMP	J:115753
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ISO	J:164563
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:88817
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:80666
Biological Process	GO:0048821	erythrocyte development	IMP	J:115753
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:163754
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:163754
Biological Process	GO:0010467	gene expression	IMP	J:241609
Biological Process	GO:0030097	hemopoiesis	IMP	J:115753
Biological Process	GO:0001701	in utero embryonic development	IMP	J:116148
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:2000726	negative regulation of cardiac muscle cell differentiation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:115753
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:116148
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:115753
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:115753
Biological Process	GO:0021778	oligodendrocyte cell fate specification	IMP	J:116148
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:116148
Biological Process	GO:0061036	positive regulation of cartilage development	ISO	J:164563
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	IDA	J:175328
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	ISO	J:164563
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:116148
Biological Process	GO:2000741	positive regulation of mesenchymal stem cell differentiation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:50394
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:50394
Biological Process	GO:0009791	post-embryonic development	IMP	J:115753
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	IMP	J:241609
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:81702
Biological Process	GO:0010468	regulation of gene expression	IMP	J:163754
Biological Process	GO:0010468	regulation of gene expression	IMP	J:163754
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	IMP	J:231103