Sp1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Sp1
trans-acting transcription factor 1
MGI:98372

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	IPI	J:178282
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:49247
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:95047
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:157160
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:50069
Molecular Function	GO:0003677	DNA binding	IDA	J:79287
Molecular Function	GO:0003677	DNA binding	IDA	J:88707
Molecular Function	GO:0003677	DNA binding	IDA	J:95370
Molecular Function	GO:0003677	DNA binding	IDA	J:87286
Molecular Function	GO:0003677	DNA binding	IDA	J:116529
Molecular Function	GO:0003677	DNA binding	ISS	J:97532
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:157160
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:300054
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:79287
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:95370
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:1587
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:94649
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:184939
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:94649
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:155856
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:261059
Molecular Function	GO:0005515	protein binding	IPI	J:65736
Molecular Function	GO:0005515	protein binding	IPI	J:94649
Molecular Function	GO:0005515	protein binding	IPI	J:94649
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:178282
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:211323
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:196264
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:126723
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:140801
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:31737
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89274
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:184939
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:63626
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:178282
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:65743
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:155856
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:196264
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0000791	euchromatin	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:261059
Cellular Component	GO:0005634	nucleus	IDA	J:79287
Cellular Component	GO:0005634	nucleus	IDA	J:63626
Cellular Component	GO:0005634	nucleus	IDA	J:99289
Cellular Component	GO:0005634	nucleus	IDA	J:102195
Cellular Component	GO:0005634	nucleus	IDA	J:94649
Cellular Component	GO:0005634	nucleus	IDA	J:49247
Cellular Component	GO:0005634	nucleus	IDA	J:90918
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:155856
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0060216	definitive hemopoiesis	IGI	J:123073
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	IGI	J:123073
Biological Process	GO:0001892	embryonic placenta development	IGI	J:123073
Biological Process	GO:0001892	embryonic placenta development	IGI	J:123073
Biological Process	GO:0060136	embryonic process involved in female pregnancy	IGI	J:123073
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:123073
Biological Process	GO:0043353	enucleate erythrocyte differentiation	IGI	J:123073
Biological Process	GO:0001701	in utero embryonic development	IGI	J:123073
Biological Process	GO:0001889	liver development	IGI	J:123073
Biological Process	GO:0030324	lung development	IGI	J:123073
Biological Process	GO:0030219	megakaryocyte differentiation	IGI	J:123073
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:184939
Biological Process	GO:0002318	myeloid progenitor cell differentiation	IGI	J:123073
Biological Process	GO:0001503	ossification	IGI	J:123073
Biological Process	GO:0043923	positive regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:211323
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:94649
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:95370
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:86236
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1904828	positive regulation of hydrogen sulfide biosynthetic process	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:285020
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:196264
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:97497
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:1587
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:261059
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:79287
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0033194	response to hydroperoxide	IDA	J:261059
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0001829	trophectodermal cell differentiation	IGI	J:123073
Biological Process	GO:0001829	trophectodermal cell differentiation	IGI	J:123073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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