GO Annotations Graph

• Symbol: Spn
• Name: sialophorin
• ID: MGI:98384

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031072	heat shock protein binding	IPI	J:240267
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:164563
Molecular Function	GO:0031072	heat shock protein binding	IBA	J:265628
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:182870
Molecular Function	GO:0005515	protein binding	IPI	J:162445
Molecular Function	GO:0005515	protein binding	IPI	J:94072
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0005604	basement membrane	IDA	J:18035
Cellular Component	GO:0005604	basement membrane	IDA	J:18035
Cellular Component	GO:0005604	basement membrane	IDA	J:18035
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0032154	cleavage furrow	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:147119
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:26220
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29272
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:63425
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:18035
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:88251
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125136
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:88252
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:29797
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:27374
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:94032
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125136
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:90603
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:98417
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:94033
Cellular Component	GO:0005615	extracellular space	ISO	J:73065
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:94032
Cellular Component	GO:0005886	plasma membrane	IDA	J:88254
Cellular Component	GO:0001931	uropod	IDA	J:283194
Cellular Component	GO:0001931	uropod	IDA	J:182870
Cellular Component	GO:0001931	uropod	IDA	J:88254
Cellular Component	GO:0001931	uropod	IDA	J:94032
Biological Process	GO:0097190	apoptotic signaling pathway	IDA	J:56164
Biological Process	GO:0007166	cell surface receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:26220
Biological Process	GO:0042742	defense response to bacterium	IBA	J:265628
Biological Process	GO:0042742	defense response to bacterium	IMP	J:63492
Biological Process	GO:0042742	defense response to bacterium	ISO	J:73065
Biological Process	GO:0050901	leukocyte tethering or rolling	IMP	J:255332
Biological Process	GO:0007162	negative regulation of cell adhesion	IDA	J:88254
Biological Process	GO:0007162	negative regulation of cell adhesion	IMP	J:88253
Biological Process	GO:0007162	negative regulation of cell adhesion	IMP	J:29272
Biological Process	GO:0050868	negative regulation of T cell activation	IMP	J:88252
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:149128
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:94033
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:29272
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:88252
Biological Process	GO:0001808	negative regulation of type IV hypersensitivity	IMP	J:88252
Biological Process	GO:0045060	negative thymic T cell selection	IMP	J:56164
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IGI	J:162445
Biological Process	GO:2000406	positive regulation of T cell migration	IMP	J:149128
Biological Process	GO:0042102	positive regulation of T cell proliferation	IDA	J:88251
Biological Process	GO:0042102	positive regulation of T cell proliferation	IDA	J:26220
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:63492
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:73065
Biological Process	GO:0006468	protein phosphorylation	IGI	J:162445
Biological Process	GO:0050688	regulation of defense response to virus	IMP	J:29272
Biological Process	GO:0050776	regulation of immune response	IBA	J:265628
Biological Process	GO:0050776	regulation of immune response	IMP	J:29272
Biological Process	GO:0050776	regulation of immune response	IMP	J:88252
Biological Process	GO:0050863	regulation of T cell activation	IEA	J:72247
Biological Process	GO:2000404	regulation of T cell migration	IMP	J:182870
Biological Process	GO:0001562	response to protozoan	IDA	J:88255
Biological Process	GO:0031295	T cell costimulation	IDA	J:88251
Biological Process	GO:0031295	T cell costimulation	IDA	J:26220
Biological Process	GO:0031295	T cell costimulation	IDA	J:56164
Biological Process	GO:0042098	T cell proliferation	IDA	J:88251
Biological Process	GO:0002296	T-helper 1 cell lineage commitment	ISO	J:164563
Biological Process	GO:0032609	type II interferon production	IEA	J:72247