GO Annotations Graph

• Symbol: Spta1
• Name: spectrin alpha, erythrocytic 1
• ID: MGI:98385

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:165884
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IBA	J:265628
Cellular Component	GO:0030864	cortical actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0032437	cuticular plate	IDA	J:157099
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IDA	J:138919
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0008091	spectrin	IMP	J:7501
Cellular Component	GO:0008091	spectrin	IMP	J:7501
Cellular Component	GO:0008091	spectrin	IMP	J:7501
Cellular Component	GO:0008091	spectrin	IMP	J:7501
Cellular Component	GO:0008091	spectrin	TAS	J:80999
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	ISO	J:164563
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7048
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7501
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7501
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7501
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7501
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7048
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	IMP	J:7048
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:19025
Biological Process	GO:0051693	actin filament capping	IEA	J:60000
Biological Process	GO:0030097	hemopoiesis	IMP	J:7048
Biological Process	GO:0030097	hemopoiesis	IMP	J:6695
Biological Process	GO:0030097	hemopoiesis	IMP	J:6695
Biological Process	GO:0030097	hemopoiesis	IMP	J:80999
Biological Process	GO:0030097	hemopoiesis	IMP	J:7048
Biological Process	GO:0030097	hemopoiesis	IMP	J:7048
Biological Process	GO:0030097	hemopoiesis	IMP	J:6695
Biological Process	GO:0030097	hemopoiesis	IMP	J:6695
Biological Process	GO:0002260	lymphocyte homeostasis	IMP	J:1967
Biological Process	GO:0007009	plasma membrane organization	IMP	J:7048
Biological Process	GO:0007009	plasma membrane organization	IMP	J:7048
Biological Process	GO:0007009	plasma membrane organization	IMP	J:7048
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	IMP	J:5985
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	IMP	J:5985
Biological Process	GO:0032092	positive regulation of protein binding	IGI	J:165884
Biological Process	GO:0032092	positive regulation of protein binding	IGI	J:165884
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:4748
Biological Process	GO:0008360	regulation of cell shape	IMP	J:19025