GO Annotations Graph

• Symbol: Sptbn1
• Name: spectrin beta, non-erythrocytic 1
• ID: MGI:98388

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:93347
Molecular Function	GO:0005515	protein binding	IPI	J:81747
Molecular Function	GO:0005515	protein binding	IPI	J:81747
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ISO	J:164563
Cellular Component	GO:0030673	axolemma	IDA	J:177866
Cellular Component	GO:0030054	cell junction	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IBA	J:265628
Cellular Component	GO:0030864	cortical actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0032437	cuticular plate	IDA	J:142574
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0031430	M band	IDA	J:93347
Cellular Component	GO:0016020	membrane	IDA	J:138919
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:81747
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:81747
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:187362
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0008091	spectrin	IEA	J:72247
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0051693	actin filament capping	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IMP	J:322307
Biological Process	GO:0007417	central nervous system development	ISO	J:164563
Biological Process	GO:0021556	central nervous system formation	ISO	J:164563
Biological Process	GO:0021556	central nervous system formation	IMP	J:322307
Biological Process	GO:0007182	common-partner SMAD protein phosphorylation	IDA	J:81747
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	ISO	J:164563
Biological Process	GO:0071709	membrane assembly	ISO	J:164563
Biological Process	GO:0000281	mitotic cytokinesis	ISO	J:164563
Biological Process	GO:0007009	plasma membrane organization	ISO	J:164563
Biological Process	GO:0032743	positive regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:124649
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0060390	regulation of SMAD protein signal transduction	IDA	J:81747