GO Annotations Graph

• Symbol: T
• Name: brachyury, T-box transcription factor T
• ID: MGI:98472

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:29824
Molecular Function	GO:0005515	protein binding	IPI	J:190269
Molecular Function	GO:0005515	protein binding	IPI	J:111703
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:190269
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:190269
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:65743
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:111703
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:14211
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:29824
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:190269
Cellular Component	GO:0000785	chromatin	IMP	J:180827
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:119027
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9754300
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756660
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756665
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756678
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756684
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9796226
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:16412
Cellular Component	GO:0005634	nucleus	IDA	J:29824
Cellular Component	GO:0005634	nucleus	IDA	J:111703
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Biological Process	GO:0009653	anatomical structure morphogenesis	IMP	J:119027
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:93195
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:93195
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:93195
Biological Process	GO:0060349	bone morphogenesis	IGI	J:65743
Biological Process	GO:0055007	cardiac muscle cell differentiation	NAS	J:175128
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	IMP	J:180827
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	ISO	J:164563
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:119027
Biological Process	GO:0061371	determination of heart left/right asymmetry	IMP	J:52218
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:16412
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:16412
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:16412
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:16412
Biological Process	GO:0048706	embryonic skeletal system development	IMP	J:16412
Biological Process	GO:0003007	heart morphogenesis	ISO	J:164563
Biological Process	GO:0003007	heart morphogenesis	IBA	J:265628
Biological Process	GO:0007498	mesoderm development	IMP	J:16412
Biological Process	GO:0001707	mesoderm formation	IBA	J:265628
Biological Process	GO:0007509	mesoderm migration involved in gastrulation	IMP	J:23779
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	IDA	J:190269
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:190269
Biological Process	GO:0001839	neural plate morphogenesis	IMP	J:93195
Biological Process	GO:0001843	neural tube closure	IMP	J:119027
Biological Process	GO:0030903	notochord development	IMP	J:16484
Biological Process	GO:0030903	notochord development	IMP	J:93195
Biological Process	GO:0030903	notochord development	IMP	J:16412
Biological Process	GO:0014028	notochord formation	IMP	J:29666
Biological Process	GO:0007341	penetration of zona pellucida	IMP	J:23636
Biological Process	GO:0007341	penetration of zona pellucida	IMP	J:23636
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:119027
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:180827
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:111703
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:5889
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:173434
Biological Process	GO:0036342	post-anal tail morphogenesis	IGI	J:65743
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:16412
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:5889
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:23779
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:29824
Biological Process	GO:0022414	reproductive process	IMP	J:5889
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:45399
Biological Process	GO:0001756	somitogenesis	IBA	J:265628
Biological Process	GO:0001756	somitogenesis	IMP	J:16412
Biological Process	GO:0001756	somitogenesis	IMP	J:93195
Biological Process	GO:0001756	somitogenesis	IMP	J:119027
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:111703
Biological Process	GO:0001570	vasculogenesis	IMP	J:119027