GO Annotations Graph

• Symbol: Tal1
• Name: T cell acute lymphocytic leukemia 1
• ID: MGI:98480

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:132709
Molecular Function	GO:0003682	chromatin binding	IDA	J:146089
Molecular Function	GO:0003682	chromatin binding	IDA	J:139179
Molecular Function	GO:0003682	chromatin binding	IDA	J:132709
Molecular Function	GO:0003682	chromatin binding	IDA	J:132709
Molecular Function	GO:0003682	chromatin binding	IDA	J:132709
Molecular Function	GO:0003682	chromatin binding	IDA	J:146089
Molecular Function	GO:0003682	chromatin binding	ISO	J:139474
Molecular Function	GO:0003682	chromatin binding	IDA	J:146089
Molecular Function	GO:0003682	chromatin binding	IDA	J:146089
Molecular Function	GO:0003682	chromatin binding	IDA	J:139179
Molecular Function	GO:0003677	DNA binding	IDA	J:118839
Molecular Function	GO:0003677	DNA binding	IDA	J:192660
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:139179
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:139179
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0070888	E-box binding	IDA	J:139179
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:118839
Molecular Function	GO:0005515	protein binding	IPI	J:150066
Molecular Function	GO:0005515	protein binding	IPI	J:200299
Molecular Function	GO:0005515	protein binding	IPI	J:155127
Molecular Function	GO:0005515	protein binding	IPI	J:155127
Molecular Function	GO:0005515	protein binding	IPI	J:202853
Molecular Function	GO:0005515	protein binding	IPI	J:70381
Molecular Function	GO:0005515	protein binding	IPI	J:87685
Molecular Function	GO:0005515	protein binding	IPI	J:155127
Molecular Function	GO:0005515	protein binding	IPI	J:147271
Molecular Function	GO:0005515	protein binding	IPI	J:102167
Molecular Function	GO:0005515	protein binding	IPI	J:147271
Molecular Function	GO:0005515	protein binding	IPI	J:147271
Molecular Function	GO:0005515	protein binding	IPI	J:92783
Molecular Function	GO:0005515	protein binding	IPI	J:160230
Molecular Function	GO:0005515	protein binding	IPI	J:147271
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:127160
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:127160
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:202853
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:127160
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:150066
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:39772
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9616215
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:118839
Cellular Component	GO:0005634	nucleus	IDA	J:150066
Cellular Component	GO:0005634	nucleus	IDA	J:146089
Cellular Component	GO:0032991	protein-containing complex	IPI	J:118839
Cellular Component	GO:0032991	protein-containing complex	IPI	J:118839
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:92783
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:147271
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:92783
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:34967
Biological Process	GO:0001525	angiogenesis	IMP	J:46127
Biological Process	GO:0001525	angiogenesis	IMP	J:98971
Biological Process	GO:0060018	astrocyte fate commitment	IMP	J:128879
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0045165	cell fate commitment	IMP	J:81796
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:128879
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:35103
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:139179
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:139179
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:149689
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:42346
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:27458
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:23061
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:98971
Biological Process	GO:0030218	erythrocyte differentiation	ISO	J:164563
Biological Process	GO:0030218	erythrocyte differentiation	TAS	J:110595
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:72727
Biological Process	GO:0030218	erythrocyte differentiation	IDA	J:72727
Biological Process	GO:0030218	erythrocyte differentiation	IDA	J:92783
Biological Process	GO:0043249	erythrocyte maturation	IMP	J:139179
Biological Process	GO:0043249	erythrocyte maturation	IMP	J:139179
Biological Process	GO:0043249	erythrocyte maturation	IMP	J:139179
Biological Process	GO:0048699	generation of neurons	IMP	J:108070
Biological Process	GO:0060217	hemangioblast cell differentiation	IMP	J:98970
Biological Process	GO:0060217	hemangioblast cell differentiation	IMP	J:146859
Biological Process	GO:0060217	hemangioblast cell differentiation	IMP	J:139179
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:98971
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:90290
Biological Process	GO:0030097	hemopoiesis	IDA	J:80834
Biological Process	GO:0007626	locomotory behavior	IMP	J:108070
Biological Process	GO:0035855	megakaryocyte development	IMP	J:139474
Biological Process	GO:0035855	megakaryocyte development	IMP	J:139474
Biological Process	GO:0030219	megakaryocyte differentiation	IMP	J:81826
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:81826
Biological Process	GO:0030099	myeloid cell differentiation	IDA	J:90266
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:102167
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:55891
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:102167
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:34967
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:55891
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:34967
Biological Process	GO:0030220	platelet formation	IMP	J:139474
Biological Process	GO:0030220	platelet formation	IMP	J:139474
Biological Process	GO:0051781	positive regulation of cell division	ISO	J:164563
Biological Process	GO:1905269	positive regulation of chromatin organization	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	IDA	J:150066
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	ISO	J:164563
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:132709
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:155127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:155127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:51482
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:92783
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:147271
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:132709
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:155127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:51482
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:132709
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:161703
Biological Process	GO:0060375	regulation of mast cell differentiation	IMP	J:149122
Biological Process	GO:0060375	regulation of mast cell differentiation	IMP	J:149122
Biological Process	GO:0045637	regulation of myeloid cell differentiation	IMP	J:139474
Biological Process	GO:0045637	regulation of myeloid cell differentiation	IMP	J:139474
Biological Process	GO:1904672	regulation of somatic stem cell population maintenance	IMP	J:156838
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:139179
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:150066
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0021527	spinal cord association neuron differentiation	IGI	J:147271
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:110595