GO Annotations Graph

• Symbol: Tap1
• Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
• ID: MGI:98483

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	EXP	J:231206
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	ISO	J:164563
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	EXP	J:231213
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0043531	ADP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:155856
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042288	MHC class I protein binding	ISO	J:155856
Molecular Function	GO:0042288	MHC class I protein binding	IPI	J:88804
Molecular Function	GO:0023029	MHC class Ib protein binding	ISO	J:164563
Molecular Function	GO:0042287	MHC protein binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	ISO	J:155856
Molecular Function	GO:0042605	peptide antigen binding	ISO	J:155856
Molecular Function	GO:0042605	peptide antigen binding	ISO	J:164563
Molecular Function	GO:1904680	peptide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:1904680	peptide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0046978	TAP1 binding	ISO	J:155856
Molecular Function	GO:0046978	TAP1 binding	IBA	J:265628
Molecular Function	GO:0046979	TAP2 binding	ISO	J:155856
Molecular Function	GO:0046979	TAP2 binding	ISO	J:164563
Molecular Function	GO:0046980	tapasin binding	ISO	J:155856
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:164563
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0030670	phagocytic vesicle membrane	TAS	Reactome:R-NUL-1236944
Cellular Component	GO:0042825	TAP complex	ISO	J:155856
Cellular Component	GO:0042825	TAP complex	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	ISO	J:164563
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	IBA	J:265628
Biological Process	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	IEA	J:72247
Biological Process	GO:0046967	cytosol to endoplasmic reticulum transport	ISO	J:164563
Biological Process	GO:0006952	defense response	IMP	J:3524
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0015833	peptide transport	ISO	J:155856
Biological Process	GO:0015833	peptide transport	ISO	J:164563
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	ISO	J:155856
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628