GO Annotations Graph

• Symbol: Hnf1b
• Name: HNF1 homeobox B
• ID: MGI:98505

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:31831
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:89193
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:87162
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:105069
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:32278
Molecular Function	GO:0003677	DNA binding	IDA	J:31593
Molecular Function	GO:0003677	DNA binding	IDA	J:32277
Molecular Function	GO:0003677	DNA binding	IDA	J:94611
Molecular Function	GO:0003677	DNA binding	IDA	J:111670
Molecular Function	GO:0003677	DNA binding	IDA	J:98014
Molecular Function	GO:0003677	DNA binding	IDA	J:31627
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:79507
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:105069
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89193
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:32278
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:94611
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:98014
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:157251
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:32278
Molecular Function	GO:0042802	identical protein binding	IPI	J:31831
Molecular Function	GO:0042802	identical protein binding	IPI	J:31593
Molecular Function	GO:0042802	identical protein binding	IPI	J:32277
Molecular Function	GO:0042802	identical protein binding	IPI	J:98014
Molecular Function	GO:0042802	identical protein binding	IPI	J:31627
Molecular Function	GO:0005515	protein binding	IPI	J:31831
Molecular Function	GO:0005515	protein binding	IPI	J:94611
Molecular Function	GO:0005515	protein binding	IPI	J:31627
Molecular Function	GO:0005515	protein binding	IPI	J:32278
Molecular Function	GO:0005515	protein binding	IPI	J:94611
Molecular Function	GO:0005515	protein binding	IPI	J:32277
Molecular Function	GO:0005515	protein binding	IPI	J:98014
Molecular Function	GO:0005515	protein binding	IPI	J:98014
Molecular Function	GO:0005515	protein binding	IPI	J:94611
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:157251
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-186679
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:94833
Cellular Component	GO:0005634	nucleus	IDA	J:31593
Cellular Component	GO:0005634	nucleus	IDA	J:111226
Cellular Component	GO:0005634	nucleus	IDA	J:32278
Cellular Component	GO:0005634	nucleus	IDA	J:95502
Cellular Component	GO:0005634	nucleus	IDA	J:31831
Cellular Component	GO:0005634	nucleus	IDA	J:31627
Cellular Component	GO:0005634	nucleus	IDA	J:89193
Cellular Component	GO:0005634	nucleus	IDA	J:98014
Cellular Component	GO:0005634	nucleus	IDA	J:113611
Cellular Component	GO:0005634	nucleus	IDA	J:94611
Cellular Component	GO:0005634	nucleus	IDA	J:32277
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:87162
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:98515
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:98515
Biological Process	GO:0006915	apoptotic process	IMP	J:139252
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IMP	J:157251
Biological Process	GO:0032922	circadian regulation of gene expression	ISO	J:155856
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	IMP	J:139252
Biological Process	GO:0048598	embryonic morphogenesis	ISO	J:155856
Biological Process	GO:0031018	endocrine pancreas development	ISO	J:164563
Biological Process	GO:0007492	endoderm development	IMP	J:139252
Biological Process	GO:0007492	endoderm development	IMP	J:58079
Biological Process	GO:0007492	endoderm development	IMP	J:58080
Biological Process	GO:0001706	endoderm formation	ISO	J:139252
Biological Process	GO:0001714	endodermal cell fate specification	IMP	J:139252
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:98014
Biological Process	GO:0060429	epithelium development	IMP	J:139252
Biological Process	GO:0048806	genitalia development	ISO	J:164563
Biological Process	GO:0061017	hepatoblast differentiation	IMP	J:139252
Biological Process	GO:0030902	hindbrain development	IMP	J:98515
Biological Process	GO:0030902	hindbrain development	IMP	J:98515
Biological Process	GO:0001826	inner cell mass cell differentiation	IMP	J:58079
Biological Process	GO:0030073	insulin secretion	IMP	J:91534
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:157251
Biological Process	GO:0060993	kidney morphogenesis	IGI	J:194051
Biological Process	GO:0001889	liver development	IMP	J:139252
Biological Process	GO:1900200	mesenchymal cell apoptotic process involved in metanephros development	IMP	J:157251
Biological Process	GO:1900200	mesenchymal cell apoptotic process involved in metanephros development	IMP	J:157251
Biological Process	GO:0072177	mesonephric duct development	IMP	J:157251
Biological Process	GO:0072181	mesonephric duct formation	IMP	J:157251
Biological Process	GO:0072164	mesonephric tubule development	IGI	J:157251
Biological Process	GO:0072164	mesonephric tubule development	IGI	J:157251
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:139252
Biological Process	GO:0061296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	IMP	J:157251
Biological Process	GO:1900212	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	IMP	J:157251
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0072176	nephric duct development	IMP	J:157251
Biological Process	GO:0072179	nephric duct formation	IMP	J:157261
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0031016	pancreas development	IEA	J:72247
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:94611
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:157251
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:98014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:89193
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:32278
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:157251
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105069
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0039020	pronephric nephron tubule development	ISO	J:164563
Biological Process	GO:0048793	pronephros development	ISO	J:164563
Biological Process	GO:0065004	protein-DNA complex assembly	ISO	J:155856
Biological Process	GO:0072095	regulation of branch elongation involved in ureteric bud branching	IMP	J:157251
Biological Process	GO:0035565	regulation of pronephros size	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IMP	J:157251
Biological Process	GO:0009749	response to glucose	IMP	J:91534
Biological Process	GO:0060677	ureteric bud elongation	IMP	J:157251