GO Annotations Graph

• Symbol: Sry
• Name: sex determining region of Chr Y
• ID: MGI:98660

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:31475
Molecular Function	GO:0008301	DNA binding, bending	IDA	J:115171
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:197716
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:103823
Molecular Function	GO:0005515	protein binding	IPI	J:164348
Molecular Function	GO:0005515	protein binding	IPI	J:75423
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:164418
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690401
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690410
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692260
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:164348
Cellular Component	GO:0005634	nucleus	IDA	J:103443
Cellular Component	GO:0005634	nucleus	IDA	J:187077
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:197716
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008584	male gonad development	IDA	J:297093
Biological Process	GO:0008584	male gonad development	IDA	J:150743
Biological Process	GO:0030238	male sex determination	IDA	J:297093
Biological Process	GO:0030238	male sex determination	IGI	J:110252
Biological Process	GO:0030238	male sex determination	IGI	J:110252
Biological Process	GO:0030238	male sex determination	IGI	J:98992
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:87729
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:164418
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:2000020	positive regulation of male gonad development	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007530	sex determination	IDA	J:297093
Biological Process	GO:0007530	sex determination	IGI	J:45884
Biological Process	GO:0007548	sex differentiation	IEA	J:60000