Symbol Name ID |
Top2a
topoisomerase (DNA) II alpha MGI:98790 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0005524 | ATP binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0008094 | ATP-dependent activity, acting on DNA | ISO | J:164563 | |||||||||
Molecular Function | GO:0003682 | chromatin binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0003682 | chromatin binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0003677 | DNA binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0003677 | DNA binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0008301 | DNA binding, bending | ISO | J:164563 | |||||||||
Molecular Function | GO:0003916 | DNA topoisomerase activity | ISO | J:155856 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | ISO | J:155856 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IDA | J:3098 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IDA | J:22850 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IDA | J:39389 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IDA | J:3098 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IGI | J:3098 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IDA | J:39389 | |||||||||
Molecular Function | GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | IGI | J:110796 | |||||||||
Molecular Function | GO:0016853 | isomerase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0000287 | magnesium ion binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0046872 | metal ion binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0000166 | nucleotide binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:198738 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:284005 | |||||||||
Molecular Function | GO:0046982 | protein heterodimerization activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0042803 | protein homodimerization activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0005080 | protein kinase C binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0043565 | sequence-specific DNA binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0043130 | ubiquitin binding | ISO | J:164563 | |||||||||
Cellular Component | GO:0005814 | centriole | ISO | J:164563 | |||||||||
Cellular Component | GO:0000775 | chromosome, centromeric region | IDA | J:240155 | |||||||||
Cellular Component | GO:0000793 | condensed chromosome | IMP | J:183026 | |||||||||
Cellular Component | GO:0000793 | condensed chromosome | IDA | J:74600 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0009330 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0009330 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex | ISO | J:155856 | |||||||||
Cellular Component | GO:0001673 | male germ cell nucleus | IDA | J:39389 | |||||||||
Cellular Component | GO:0001673 | male germ cell nucleus | IDA | J:39389 | |||||||||
Cellular Component | GO:0000228 | nuclear chromosome | ISO | J:164563 | |||||||||
Cellular Component | GO:0005730 | nucleolus | ISO | J:155856 | |||||||||
Cellular Component | GO:0005730 | nucleolus | IDA | J:74600 | |||||||||
Cellular Component | GO:0005654 | nucleoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005654 | nucleoplasm | TAS | Reactome:R-MMU-5228515 | |||||||||
Cellular Component | GO:0005634 | nucleus | ISO | J:164563 | |||||||||
Cellular Component | GO:0005634 | nucleus | ISO | J:155856 | |||||||||
Cellular Component | GO:0005634 | nucleus | IBA | J:265628 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:233467 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:42077 | |||||||||
Cellular Component | GO:0032991 | protein-containing complex | ISO | J:164563 | |||||||||
Cellular Component | GO:1990904 | ribonucleoprotein complex | ISO | J:164563 | |||||||||
Biological Process | GO:0030263 | apoptotic chromosome condensation | ISO | J:164563 | |||||||||
Biological Process | GO:0030263 | apoptotic chromosome condensation | IBA | J:265628 | |||||||||
Biological Process | GO:0030261 | chromosome condensation | IMP | J:74620 | |||||||||
Biological Process | GO:0007059 | chromosome segregation | ISO | J:164563 | |||||||||
Biological Process | GO:0007059 | chromosome segregation | IMP | J:74620 | |||||||||
Biological Process | GO:0007059 | chromosome segregation | IDA | J:22850 | |||||||||
Biological Process | GO:0006974 | DNA damage response | ISO | J:164563 | |||||||||
Biological Process | GO:0006266 | DNA ligation | ISO | J:164563 | |||||||||
Biological Process | GO:0006259 | DNA metabolic process | IEA | J:72247 | |||||||||
Biological Process | GO:0006265 | DNA topological change | ISO | J:164563 | |||||||||
Biological Process | GO:0006265 | DNA topological change | ISO | J:155856 | |||||||||
Biological Process | GO:0006265 | DNA topological change | IDA | J:42077 | |||||||||
Biological Process | GO:0006265 | DNA topological change | IDA | J:3098 | |||||||||
Biological Process | GO:0040016 | embryonic cleavage | IMP | J:74620 | |||||||||
Biological Process | GO:0051309 | female meiosis chromosome separation | TAS | J:233467 | |||||||||
Biological Process | GO:0007143 | female meiotic nuclear division | IMP | J:233467 | |||||||||
Biological Process | GO:0002244 | hematopoietic progenitor cell differentiation | IMP | J:202604 | |||||||||
Biological Process | GO:1905463 | negative regulation of DNA duplex unwinding | ISO | J:164563 | |||||||||
Biological Process | GO:0043065 | positive regulation of apoptotic process | ISO | J:164563 | |||||||||
Biological Process | GO:0045870 | positive regulation of single stranded viral RNA replication via double stranded DNA intermediate | ISO | J:164563 | |||||||||
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | IMP | J:1777 | |||||||||
Biological Process | GO:0042752 | regulation of circadian rhythm | IMP | J:217257 | |||||||||
Biological Process | GO:0000712 | resolution of meiotic recombination intermediates | IBA | J:265628 | |||||||||
Biological Process | GO:0048511 | rhythmic process | IEA | J:60000 | |||||||||
Biological Process | GO:0000819 | sister chromatid segregation | IBA | J:265628 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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