GO Annotations Graph

• Symbol: Hsp90b1
• Name: heat shock protein 90, beta (Grp94), member 1
• ID: MGI:98817

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:90197
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:167004
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0044183	protein folding chaperone	ISO	J:327398
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:142802
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:268046
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:78076
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:92989
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IDA	J:217288
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:164563
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:327398
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2173779
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0016529	sarcoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0097524	sperm plasma membrane	IDA	J:91263
Biological Process	GO:0031247	actin rod assembly	ISO	J:142802
Biological Process	GO:0071318	cellular response to ATP	ISO	J:142802
Biological Process	GO:0030070	insulin processing	ISO	J:327398
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	ISO	J:142802
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628