Trp53 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Trp53
transformation related protein 53
MGI:98834

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0036310	ATP-dependent DNA/DNA annealing activity	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:160291
Molecular Function	GO:0003682	chromatin binding	IDA	J:96056
Molecular Function	GO:0003682	chromatin binding	ISO	J:73065
Molecular Function	GO:0003682	chromatin binding	IDA	J:136812
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0005507	copper ion binding	ISO	J:164563
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IGI	J:115191
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:167598
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:171002
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:104726
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:106848
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:78076
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0140296	general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0035033	histone deacetylase regulator activity	IDA	J:96056
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0097371	MDM2/MDM4 family protein binding	IPI	J:170216
Molecular Function	GO:0097371	MDM2/MDM4 family protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0003730	mRNA 3'-UTR binding	ISO	J:164563
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:190273
Molecular Function	GO:0005515	protein binding	IPI	J:114015
Molecular Function	GO:0005515	protein binding	IPI	J:289079
Molecular Function	GO:0005515	protein binding	IPI	J:176251
Molecular Function	GO:0005515	protein binding	IPI	J:285022
Molecular Function	GO:0005515	protein binding	IPI	J:182493
Molecular Function	GO:0005515	protein binding	IPI	J:277853
Molecular Function	GO:0005515	protein binding	IPI	J:214218
Molecular Function	GO:0005515	protein binding	IPI	J:213900
Molecular Function	GO:0005515	protein binding	IPI	J:240382
Molecular Function	GO:0005515	protein binding	IPI	J:175358
Molecular Function	GO:0005515	protein binding	IPI	J:182417
Molecular Function	GO:0005515	protein binding	IPI	J:177154
Molecular Function	GO:0005515	protein binding	IPI	J:133357
Molecular Function	GO:0005515	protein binding	IPI	J:172901
Molecular Function	GO:0005515	protein binding	IPI	J:135538
Molecular Function	GO:0005515	protein binding	IPI	J:177242
Molecular Function	GO:0005515	protein binding	IPI	J:247427
Molecular Function	GO:0005515	protein binding	IPI	J:247429
Molecular Function	GO:0005515	protein binding	IPI	J:174543
Molecular Function	GO:0005515	protein binding	IPI	J:150816
Molecular Function	GO:0005515	protein binding	IPI	J:150816
Molecular Function	GO:0005515	protein binding	IPI	J:273523
Molecular Function	GO:0005515	protein binding	IPI	J:72328
Molecular Function	GO:0005515	protein binding	IPI	J:156082
Molecular Function	GO:0005515	protein binding	IPI	J:201306
Molecular Function	GO:0005515	protein binding	IPI	J:269561
Molecular Function	GO:0005515	protein binding	IPI	J:126004
Molecular Function	GO:0005515	protein binding	IPI	J:164200
Molecular Function	GO:0005515	protein binding	IPI	J:164395
Molecular Function	GO:0005515	protein binding	IPI	J:191729
Molecular Function	GO:0005515	protein binding	IPI	J:200441
Molecular Function	GO:0005515	protein binding	IPI	J:170004
Molecular Function	GO:0005515	protein binding	IPI	J:248554
Molecular Function	GO:0005515	protein binding	IPI	J:200506
Molecular Function	GO:0005515	protein binding	IPI	J:245312
Molecular Function	GO:0005515	protein binding	IPI	J:210943
Molecular Function	GO:0005515	protein binding	IPI	J:94782
Molecular Function	GO:0005515	protein binding	IPI	J:99711
Molecular Function	GO:0005515	protein binding	IPI	J:124168
Molecular Function	GO:0005515	protein binding	IPI	J:94782
Molecular Function	GO:0005515	protein binding	IPI	J:136033
Molecular Function	GO:0005515	protein binding	IPI	J:101198
Molecular Function	GO:0005515	protein binding	IPI	J:150303
Molecular Function	GO:0005515	protein binding	IPI	J:75893
Molecular Function	GO:0005515	protein binding	IPI	J:164679
Molecular Function	GO:0005515	protein binding	IPI	J:75464
Molecular Function	GO:0005515	protein binding	IPI	J:186254
Molecular Function	GO:0005515	protein binding	IPI	J:96269
Molecular Function	GO:0005515	protein binding	IPI	J:124168
Molecular Function	GO:0005515	protein binding	IPI	J:98384
Molecular Function	GO:0005515	protein binding	IPI	J:124168
Molecular Function	GO:0005515	protein binding	IPI	J:63419
Molecular Function	GO:0005515	protein binding	IPI	J:90012
Molecular Function	GO:0005515	protein binding	IPI	J:55013
Molecular Function	GO:0005515	protein binding	IPI	J:92518
Molecular Function	GO:0005515	protein binding	IPI	J:54842
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:217260
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:201153
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:54842
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:100764
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:54842
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:187177
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:78076
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:167598
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:104687
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:202649
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001221	transcription coregulator binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:265621
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISS	J:276406
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:75464
Cellular Component	GO:0005737	cytoplasm	IDA	J:75893
Cellular Component	GO:0005737	cytoplasm	IDA	J:81445
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:75464
Cellular Component	GO:0005829	cytosol	ISO	J:201969
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0043073	germ cell nucleus	IDA	J:81445
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:186254
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:182408
Cellular Component	GO:0005739	mitochondrion	ISO	J:201969
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:240382
Cellular Component	GO:0005634	nucleus	IDA	J:219625
Cellular Component	GO:0005634	nucleus	IDA	J:277981
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:124168
Cellular Component	GO:0005634	nucleus	IDA	J:75893
Cellular Component	GO:0005634	nucleus	ISO	J:141360
Cellular Component	GO:0005634	nucleus	IDA	J:136033
Cellular Component	GO:0005634	nucleus	IDA	J:75464
Cellular Component	GO:0005634	nucleus	IDA	J:87744
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	ISO	J:201969
Cellular Component	GO:0005634	nucleus	IDA	J:137150
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0016605	PML body	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0005657	replication fork	IDA	J:92518
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:155856
Cellular Component	GO:0035861	site of double-strand break	IDA	J:206795
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IMP	J:122494
Biological Process	GO:0006915	apoptotic process	IMP	J:130019
Biological Process	GO:0006915	apoptotic process	IDA	J:101402
Biological Process	GO:0006915	apoptotic process	IGI	J:121357
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0002326	B cell lineage commitment	IMP	J:31364
Biological Process	GO:0048539	bone marrow development	ISO	J:164563
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0060411	cardiac septum morphogenesis	IGI	J:188490
Biological Process	GO:0060411	cardiac septum morphogenesis	IGI	J:188490
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	IGI	J:64364
Biological Process	GO:0072717	cellular response to actinomycin D	ISO	J:164563
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:164563
Biological Process	GO:0071480	cellular response to gamma radiation	IDA	J:60946
Biological Process	GO:0042149	cellular response to glucose starvation	ISO	J:73065
Biological Process	GO:0071479	cellular response to ionizing radiation	IDA	J:240282
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:164563
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0034614	cellular response to reactive oxygen species	ISO	J:155856
Biological Process	GO:0033554	cellular response to stress	IGI	J:224364
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	IDA	J:197027
Biological Process	GO:0034644	cellular response to UV	IGI	J:90012
Biological Process	GO:0071494	cellular response to UV-C	IGI	J:204913
Biological Process	GO:0090398	cellular senescence	ISO	J:164563
Biological Process	GO:0007417	central nervous system development	IGI	J:101353
Biological Process	GO:0021549	cerebellum development	IDA	J:201153
Biological Process	GO:0051276	chromosome organization	IGI	J:115639
Biological Process	GO:0051276	chromosome organization	IGI	J:115639
Biological Process	GO:0051276	chromosome organization	IGI	J:117211
Biological Process	GO:0048512	circadian behavior	IMP	J:217260
Biological Process	GO:0007623	circadian rhythm	IEP	J:217260
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:170216
Biological Process	GO:0006974	DNA damage response	IMP	J:124168
Biological Process	GO:0006974	DNA damage response	IMP	J:115386
Biological Process	GO:0006974	DNA damage response	IMP	J:85569
Biological Process	GO:0006974	DNA damage response	IDA	J:88275
Biological Process	GO:0006974	DNA damage response	IDA	J:93432
Biological Process	GO:0006974	DNA damage response	ISO	J:73065
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	IDA	J:88409
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	IDA	J:73858
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	IGI	J:101353
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	IGI	J:122559
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	ISO	J:164563
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	IGI	J:100764
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	ISO	J:164563
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	IDA	J:60946
Biological Process	GO:0006302	double-strand break repair	IMP	J:130019
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	IGI	J:108701
Biological Process	GO:0048568	embryonic organ development	IGI	J:121586
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	IMP	J:217260
Biological Process	GO:0006983	ER overload response	ISO	J:73065
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:127492
Biological Process	GO:0048144	fibroblast proliferation	IGI	J:100764
Biological Process	GO:0007369	gastrulation	IGI	J:117590
Biological Process	GO:0014009	glial cell proliferation	IGI	J:80411
Biological Process	GO:0014009	glial cell proliferation	IGI	J:64364
Biological Process	GO:0019661	glucose catabolic process to lactate via pyruvate	IMP	J:167245
Biological Process	GO:0007507	heart development	IGI	J:188490
Biological Process	GO:0007507	heart development	IGI	J:188490
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0060218	hematopoietic stem cell differentiation	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IGI	J:42723
Biological Process	GO:0001701	in utero embryonic development	IGI	J:121357
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IDA	J:240382
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IDA	J:78076
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IDA	J:100764
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IGI	J:160291
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IDA	J:240282
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:170216
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IGI	J:122559
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:111068
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO	J:73065
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IGI	J:115191
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:85569
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IGI	J:99862
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO	J:87001
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:78076
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IGI	J:99862
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:219625
Biological Process	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia	IMP	J:167245
Biological Process	GO:0043504	mitochondrial DNA repair	IMP	J:201969
Biological Process	GO:0000423	mitophagy	IMP	J:183674
Biological Process	GO:0000423	mitophagy	IMP	J:183674
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	IMP	J:100764
Biological Process	GO:0009299	mRNA transcription	ISO	J:164563
Biological Process	GO:0035264	multicellular organism growth	IGI	J:121357
Biological Process	GO:0035264	multicellular organism growth	IGI	J:120961
Biological Process	GO:0070266	necroptotic process	IGI	J:186254
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:130019
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:18753
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:172952
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:58876
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:204457
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:155856
Biological Process	GO:0008156	negative regulation of DNA replication	IDA	J:88409
Biological Process	GO:0008156	negative regulation of DNA replication	IMP	J:88409
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:217260
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:172952
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:197027
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:127492
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:85569
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IGI	J:100764
Biological Process	GO:1903451	negative regulation of G1 to G0 transition	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	IGI	J:138546
Biological Process	GO:0060253	negative regulation of glial cell proliferation	IGI	J:80411
Biological Process	GO:0060253	negative regulation of glial cell proliferation	IGI	J:64364
Biological Process	GO:1904024	negative regulation of glucose catabolic process to lactate via pyruvate	IMP	J:167245
Biological Process	GO:1903799	negative regulation of miRNA processing	IGI	J:173189
Biological Process	GO:1901525	negative regulation of mitophagy	IMP	J:183674
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	IGI	J:32537
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	IGI	J:47680
Biological Process	GO:1905856	negative regulation of pentose-phosphate shunt	ISO	J:164563
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:193629
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:58877
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:172952
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:136812
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:150303
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:96056
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:18753
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IMP	J:96056
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:47680
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:47680
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:47680
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:124168
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63078
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:66953
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:115386
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:94157
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0097252	oligodendrocyte apoptotic process	ISO	J:164563
Biological Process	GO:0090403	oxidative stress-induced premature senescence	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:124814
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:111678
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:111678
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:38331
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	IMP	J:183674
Biological Process	GO:0045787	positive regulation of cell cycle	ISO	J:155856
Biological Process	GO:2000774	positive regulation of cellular senescence	IMP	J:175124
Biological Process	GO:2000774	positive regulation of cellular senescence	ISO	J:164563
Biological Process	GO:2000774	positive regulation of cellular senescence	IGI	J:115639
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:104726
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGI	J:98384
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:98384
Biological Process	GO:1900119	positive regulation of execution phase of apoptosis	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0002687	positive regulation of leukocyte migration	ISO	J:155856
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0035794	positive regulation of mitochondrial membrane permeability	IGI	J:186254
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:97170
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:66953
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:47680
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IGI	J:63078
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IGI	J:111068
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IDA	J:63419
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:115386
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:172952
Biological Process	GO:0062100	positive regulation of programmed necrotic cell death	IMP	J:259866
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	ISO	J:164563
Biological Process	GO:0070245	positive regulation of thymocyte apoptotic process	IMP	J:170216
Biological Process	GO:0070245	positive regulation of thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:150303
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:167598
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:160291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:167598
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:106848
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:100764
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182131
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:28974
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:18753
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:162584
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	IMP	J:219625
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	IMP	J:167245
Biological Process	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	ISS	J:276406
Biological Process	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	IDA	J:240382
Biological Process	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	ISO	J:164563
Biological Process	GO:0012501	programmed cell death	IEA	J:60000
Biological Process	GO:0006606	protein import into nucleus	IDA	J:75464
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	IGI	J:138546
Biological Process	GO:0051262	protein tetramerization	IEA	J:72247
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:183674
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:73065
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:155856
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:99580
Biological Process	GO:0051726	regulation of cell cycle	IGI	J:136033
Biological Process	GO:1902749	regulation of cell cycle G2/M phase transition	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:84791
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:61200
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:62221
Biological Process	GO:2000772	regulation of cellular senescence	IGI	J:199753
Biological Process	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	IGI	J:173189
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:78076
Biological Process	GO:2000269	regulation of fibroblast apoptotic process	IGI	J:120961
Biological Process	GO:1903205	regulation of hydrogen peroxide-induced cell death	ISO	J:155856
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:155856
Biological Process	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:141360
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	IGI	J:90012
Biological Process	GO:0007346	regulation of mitotic cell cycle	IDA	J:123623
Biological Process	GO:0043523	regulation of neuron apoptotic process	IGI	J:97170
Biological Process	GO:0070243	regulation of thymocyte apoptotic process	IGI	J:118992
Biological Process	GO:0034103	regulation of tissue remodeling	IMP	J:183674
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:201153
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IDA	J:97170
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IGI	J:90012
Biological Process	GO:0090399	replicative senescence	ISO	J:164563
Biological Process	GO:0010332	response to gamma radiation	ISO	J:164563
Biological Process	GO:0010332	response to gamma radiation	IMP	J:124814
Biological Process	GO:0010332	response to gamma radiation	IDA	J:88275
Biological Process	GO:0010035	response to inorganic substance	IMP	J:122494
Biological Process	GO:0002931	response to ischemia	IMP	J:183674
Biological Process	GO:0006979	response to oxidative stress	IMP	J:124168
Biological Process	GO:0006979	response to oxidative stress	IGI	J:186254
Biological Process	GO:0009651	response to salt stress	IGI	J:111678
Biological Process	GO:0009651	response to salt stress	IGI	J:111678
Biological Process	GO:0009411	response to UV	IDA	J:88275
Biological Process	GO:0009411	response to UV	IMP	J:85569
Biological Process	GO:0009411	response to UV	IMP	J:115386
Biological Process	GO:0009411	response to UV	IMP	J:62429
Biological Process	GO:0010165	response to X-ray	ISO	J:155856
Biological Process	GO:0010165	response to X-ray	IDA	J:88409
Biological Process	GO:0010165	response to X-ray	IMP	J:188490
Biological Process	GO:0009410	response to xenobiotic stimulus	IDA	J:40102
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0009303	rRNA transcription	IGI	J:142821
Biological Process	GO:0072331	signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:0001756	somitogenesis	IGI	J:121359
Biological Process	GO:0007283	spermatogenesis	ISO	J:155856
Biological Process	GO:0072089	stem cell proliferation	IGI	J:58877
Biological Process	GO:0033077	T cell differentiation in thymus	IGI	J:103921
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0002360	T cell lineage commitment	IMP	J:31364
Biological Process	GO:0002309	T cell proliferation involved in immune response	IGI	J:103921
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:118992
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:136812
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:136812
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:136812
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0060333	type II interferon-mediated signaling pathway	IMP	J:197027
Biological Process	GO:0016032	viral process	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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