GO Annotations Graph

• Symbol: Tshr
• Name: thyroid stimulating hormone receptor
• ID: MGI:98849

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0016500	protein-hormone receptor activity	IEA	J:72247
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:164563
Molecular Function	GO:0004996	thyroid-stimulating hormone receptor activity	ISO	J:164563
Molecular Function	GO:0004996	thyroid-stimulating hormone receptor activity	ISO	J:155856
Molecular Function	GO:0004996	thyroid-stimulating hormone receptor activity	IBA	J:265628
Molecular Function	GO:0004996	thyroid-stimulating hormone receptor activity	IDA	J:70498
Molecular Function	GO:0004996	thyroid-stimulating hormone receptor activity	IDA	J:26725
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:26725
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:70498
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:85902
Biological Process	GO:0030183	B cell differentiation	IMP	J:110683
Biological Process	GO:0007166	cell surface receptor signaling pathway	ISO	J:164563
Biological Process	GO:1904588	cellular response to glycoprotein	ISO	J:164563
Biological Process	GO:1905229	cellular response to thyrotropin-releasing hormone	ISO	J:164563
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:110962
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:110962
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0060119	inner ear receptor cell development	IMP	J:110962
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IMP	J:110962
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:139995
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:85902
Biological Process	GO:0040012	regulation of locomotion	IMP	J:85902
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0038194	thyroid-stimulating hormone signaling pathway	IDA	J:26725
Biological Process	GO:0038194	thyroid-stimulating hormone signaling pathway	ISO	J:164563