GO Annotations Graph

• Symbol: Vav1
• Name: vav 1 oncogene
• ID: MGI:98923

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	EXP	J:105055
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	EXP	J:102491
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	EXP	J:266120
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IGI	J:91862
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140031	phosphorylation-dependent protein binding	IPI	J:76319
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:245280
Molecular Function	GO:0005515	protein binding	IPI	J:189787
Molecular Function	GO:0005515	protein binding	IPI	J:31423
Molecular Function	GO:0005515	protein binding	IPI	J:189787
Molecular Function	GO:0005515	protein binding	IPI	J:189787
Molecular Function	GO:0005515	protein binding	IPI	J:189787
Molecular Function	GO:0005515	protein binding	IPI	J:148303
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-434629
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-434634
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029152
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9029162
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9607042
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IGI	J:168922
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IGI	J:168922
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IGI	J:168922
Biological Process	GO:0006955	immune response	IMP	J:79550
Biological Process	GO:0007229	integrin-mediated signaling pathway	IGI	J:91862
Biological Process	GO:0035556	intracellular signal transduction	IMP	J:79550
Biological Process	GO:0030593	neutrophil chemotaxis	IGI	J:168922
Biological Process	GO:0006909	phagocytosis	IGI	J:91862
Biological Process	GO:0045785	positive regulation of cell adhesion	IGI	J:91862
Biological Process	GO:0045785	positive regulation of cell adhesion	IGI	J:168922
Biological Process	GO:0043547	positive regulation of GTPase activity	IGI	J:168922
Biological Process	GO:0043547	positive regulation of GTPase activity	IGI	J:168922
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IGI	J:166054
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IGI	J:166054
Biological Process	GO:0072593	reactive oxygen species metabolic process	IGI	J:168922
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IGI	J:91862
Biological Process	GO:0007264	small GTPase mediated signal transduction	IEA	J:72247
Biological Process	GO:0042110	T cell activation	IMP	J:79550
Biological Process	GO:0030217	T cell differentiation	IGI	J:168922
Biological Process	GO:0030217	T cell differentiation	TAS	J:79550