GO Annotations Graph

• Symbol: Vip
• Name: vasoactive intestinal polypeptide
• ID: MGI:98933

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	ISO	J:155856
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	IDA	J:183231
Molecular Function	GO:0005184	neuropeptide hormone activity	IBA	J:265628
Molecular Function	GO:0051428	peptide hormone receptor binding	ISO	J:164563
Molecular Function	GO:0051428	peptide hormone receptor binding	IBA	J:265628
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:183231
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0019732	antifungal humoral response	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0048242	epinephrine secretion	IBA	J:265628
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0007611	learning or memory	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0043267	negative regulation of potassium ion transport	ISO	J:155856
Biological Process	GO:0043267	negative regulation of potassium ion transport	IBA	J:265628
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	IBA	J:265628
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0032812	positive regulation of epinephrine secretion	IBA	J:265628
Biological Process	GO:0060406	positive regulation of penile erection	ISO	J:155856
Biological Process	GO:0060406	positive regulation of penile erection	IBA	J:265628
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0045732	positive regulation of protein catabolic process	IDA	J:183231
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:155856
Biological Process	GO:0045732	positive regulation of protein catabolic process	IBA	J:265628
Biological Process	GO:0032880	regulation of protein localization	IDA	J:183231
Biological Process	GO:0032880	regulation of protein localization	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	IBA	J:265628
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0051930	regulation of sensory perception of pain	IBA	J:265628
Biological Process	GO:0009966	regulation of signal transduction	IMP	J:176173
Biological Process	GO:0001878	response to yeast	ISO	J:164563