GO Annotations Graph

• Symbol: Vldlr
• Name: very low density lipoprotein receptor
• ID: MGI:98935

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:164563
Molecular Function	GO:0034185	apolipoprotein binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0038024	cargo receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:91679
Molecular Function	GO:0038025	reelin receptor activity	IGI	J:142541
Molecular Function	GO:0038025	reelin receptor activity	IMP	J:142541
Molecular Function	GO:0034189	very-low-density lipoprotein particle binding	ISO	J:164563
Molecular Function	GO:0030229	very-low-density lipoprotein particle receptor activity	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005905	clathrin-coated pit	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:131467
Cellular Component	GO:0016020	membrane	ISO	J:90197
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0034361	very-low-density lipoprotein particle	IEA	J:60000
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:155856
Biological Process	GO:0008203	cholesterol metabolic process	IEA	J:60000
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:142541
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0034436	glycoprotein transport	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:1900006	positive regulation of dendrite development	IGI	J:142541
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:109819
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:109819
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0038026	reelin-mediated signaling pathway	IGI	J:142541
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0021517	ventral spinal cord development	IEP	J:166792
Biological Process	GO:0034447	very-low-density lipoprotein particle clearance	ISO	J:164563