GO Annotations Graph

• Symbol: Vwf
• Name: Von Willebrand factor
• ID: MGI:98941

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005518	collagen binding	ISO	J:164563
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0019865	immunoglobulin binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:134343
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:125139
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:295079
Cellular Component	GO:0033093	Weibel-Palade body	ISO	J:164563
Cellular Component	GO:0033093	Weibel-Palade body	IDA	J:295079
Biological Process	GO:0002543	activation of blood coagulation via clotting cascade	IDA	J:295079
Biological Process	GO:0007596	blood coagulation	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	ISO	J:155856
Biological Process	GO:0007596	blood coagulation	IBA	J:265628
Biological Process	GO:0007596	blood coagulation	IMP	J:121278
Biological Process	GO:0007596	blood coagulation	IMP	J:168396
Biological Process	GO:0007596	blood coagulation	IMP	J:49083
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0031589	cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0031589	cell-substrate adhesion	IBA	J:265628
Biological Process	GO:0031589	cell-substrate adhesion	IMP	J:65812
Biological Process	GO:0007599	hemostasis	ISO	J:164563
Biological Process	GO:0007599	hemostasis	TAS	J:59403
Biological Process	GO:0007599	hemostasis	IMP	J:49083
Biological Process	GO:0006954	inflammatory response	IDA	J:295079
Biological Process	GO:0001889	liver development	IMP	J:23170
Biological Process	GO:0001890	placenta development	IMP	J:23170
Biological Process	GO:0030168	platelet activation	IMP	J:63750
Biological Process	GO:0030168	platelet activation	IMP	J:168396
Biological Process	GO:1902533	positive regulation of intracellular signal transduction	ISO	J:164563