GO Annotations Graph

• Symbol: Wnt2
• Name: wingless-type MMTV integration site family, member 2
• ID: MGI:98954

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	ISO	J:164563
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IEA	J:72247
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:197681
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	IMP	J:158582
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:153098
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:48026
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:158582
Biological Process	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	ISO	J:164563
Biological Process	GO:0060317	cardiac epithelial to mesenchymal transition	IMP	J:158582
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:158582
Biological Process	GO:0060038	cardiac muscle cell proliferation	IMP	J:158582
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0033278	cell proliferation in midbrain	ISO	J:164563
Biological Process	GO:0033278	cell proliferation in midbrain	IMP	J:161745
Biological Process	GO:0007267	cell-cell signaling	ISO	J:164563
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:153098
Biological Process	GO:0060502	epithelial cell proliferation involved in lung morphogenesis	IMP	J:153098
Biological Process	GO:0060502	epithelial cell proliferation involved in lung morphogenesis	IMP	J:153098
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:36835
Biological Process	GO:0060492	lung induction	IGI	J:153098
Biological Process	GO:0010463	mesenchymal cell proliferation	IMP	J:153098
Biological Process	GO:1904948	midbrain dopaminergic neuron differentiation	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:158582
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:153098
Biological Process	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	IMP	J:153098
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	IMP	J:153098
Biological Process	GO:0050769	positive regulation of neurogenesis	IDA	J:161745
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:158582
Biological Process	GO:0016055	Wnt signaling pathway	IGI	J:52605