Wnt3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Wnt3
wingless-type MMTV integration site family, member 3
MGI:98955

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	ISO	J:164563
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:123536
Molecular Function	GO:0005515	protein binding	IPI	J:154679
Molecular Function	GO:0005515	protein binding	IPI	J:63226
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:142801
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	TAS	J:52010
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-3238692
Cellular Component	GO:0031012	extracellular matrix	IDA	J:21428
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:56511
Biological Process	GO:0009887	animal organ morphogenesis	TAS	J:52010
Biological Process	GO:0009948	anterior/posterior axis specification	IMP	J:130205
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:56511
Biological Process	GO:0007411	axon guidance	IDA	J:138829
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:134688
Biological Process	GO:0044338	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	ISO	J:164563
Biological Process	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	ISO	J:164563
Biological Process	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation	ISO	J:164563
Biological Process	GO:1905474	canonical Wnt signaling pathway involved in stem cell proliferation	ISO	J:164563
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0000902	cell morphogenesis	ISO	J:164563
Biological Process	GO:0007267	cell-cell signaling	TAS	J:52010
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:81795
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:81795
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:81795
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:81795
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:81795
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:81795
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:81795
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:81795
Biological Process	GO:0007276	gamete generation	IGI	J:199855
Biological Process	GO:0010467	gene expression	IDA	J:152705
Biological Process	GO:0060323	head morphogenesis	IGI	J:134688
Biological Process	GO:0060174	limb bud formation	ISO	J:164563
Biological Process	GO:0060173	limb development	IMP	J:81795
Biological Process	GO:0060173	limb development	IMP	J:81795
Biological Process	GO:0060173	limb development	IMP	J:81795
Biological Process	GO:0060173	limb development	IMP	J:81795
Biological Process	GO:0001707	mesoderm formation	IMP	J:56511
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	IDA	J:138829
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0048697	positive regulation of collateral sprouting in absence of injury	IDA	J:138829
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:152705
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IDA	J:193686
Biological Process	GO:0050767	regulation of neurogenesis	ISO	J:164563
Biological Process	GO:0007165	signal transduction	TAS	J:52010
Biological Process	GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	IMP	J:56511
Biological Process	GO:0072089	stem cell proliferation	ISO	J:164563
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:72247
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24