Wt1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Wt1
WT1 transcription factor
MGI:98968

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	ISS	J:155220
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:180645
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:175204
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:155370
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0003690	double-stranded DNA binding	IDA	J:30176
Molecular Function	GO:0010385	double-stranded methylated DNA binding	ISO	J:164563
Molecular Function	GO:0044729	hemi-methylated DNA-binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:219967
Molecular Function	GO:0005515	protein binding	IPI	J:156042
Molecular Function	GO:0005515	protein binding	IPI	J:156080
Molecular Function	GO:0005515	protein binding	IPI	J:135126
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISS	J:155220
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:87376
Cellular Component	GO:0005737	cytoplasm	IDA	J:87376
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	TAS	J:156080
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692234
Cellular Component	GO:0005634	nucleus	IDA	J:175204
Cellular Component	GO:0005634	nucleus	IDA	J:156235
Cellular Component	GO:0005634	nucleus	IDA	J:132868
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:156042
Cellular Component	GO:0005634	nucleus	IDA	J:247929
Biological Process	GO:0035802	adrenal cortex formation	IMP	J:135126
Biological Process	GO:0030325	adrenal gland development	IMP	J:52756
Biological Process	GO:0030325	adrenal gland development	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IMP	J:104620
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	ISO	J:164563
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:52756
Biological Process	GO:0043010	camera-type eye development	IMP	J:75445
Biological Process	GO:0060923	cardiac muscle cell fate commitment	IMP	J:175370
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	ISO	J:164563
Biological Process	GO:0060976	coronary vasculature development	TAS	J:169941
Biological Process	GO:0060539	diaphragm development	IMP	J:14317
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:52959
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:104620
Biological Process	GO:0007281	germ cell development	IMP	J:92201
Biological Process	GO:0032836	glomerular basement membrane development	ISO	J:164563
Biological Process	GO:0032835	glomerulus development	ISO	J:164563
Biological Process	GO:0032835	glomerulus development	IMP	J:52756
Biological Process	GO:0008406	gonad development	IMP	J:14317
Biological Process	GO:0007507	heart development	IMP	J:52756
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:118413
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0030539	male genitalia development	IMP	J:53585
Biological Process	GO:0008584	male gonad development	IMP	J:104620
Biological Process	GO:0008584	male gonad development	IGI	J:150743
Biological Process	GO:0008584	male gonad development	IMP	J:92201
Biological Process	GO:1900200	mesenchymal cell apoptotic process involved in metanephros development	IMP	J:14317
Biological Process	GO:1900200	mesenchymal cell apoptotic process involved in metanephros development	IMP	J:14317
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:52959
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:14317
Biological Process	GO:0001823	mesonephros development	IMP	J:40389
Biological Process	GO:0072278	metanephric comma-shaped body morphogenesis	IEP	J:138858
Biological Process	GO:0072075	metanephric mesenchyme development	IMP	J:14317
Biological Process	GO:0072284	metanephric S-shaped body morphogenesis	IMP	J:52756
Biological Process	GO:0072284	metanephric S-shaped body morphogenesis	ISO	J:164563
Biological Process	GO:0072284	metanephric S-shaped body morphogenesis	IEP	J:138858
Biological Process	GO:0001656	metanephros development	IMP	J:14317
Biological Process	GO:0001656	metanephros development	IMP	J:54493
Biological Process	GO:0001656	metanephros development	IMP	J:71149
Biological Process	GO:0001656	metanephros development	IMP	J:54493
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:52756
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISS	J:156235
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISS	J:155220
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:155370
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2000195	negative regulation of female gonad development	IMP	J:147038
Biological Process	GO:1900212	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	IMP	J:14317
Biological Process	GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	IMP	J:53585
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:30176
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:0072015	podocyte development	IEP	J:138858
Biological Process	GO:0072112	podocyte differentiation	IDA	J:156042
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1905643	positive regulation of DNA methylation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:118413
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:147038
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:52959
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:155370
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:135126
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0060421	positive regulation of heart growth	IMP	J:14317
Biological Process	GO:2000020	positive regulation of male gonad development	IMP	J:147038
Biological Process	GO:2001076	positive regulation of metanephric ureteric bud development	IMP	J:14317
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:180645
Biological Process	GO:0072166	posterior mesonephric tubule development	IMP	J:40389
Biological Process	GO:0003156	regulation of animal organ formation	IMP	J:135126
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:75445
Biological Process	GO:0010468	regulation of gene expression	IMP	J:104620
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:78371
Biological Process	GO:0008380	RNA splicing	IDA	J:156080
Biological Process	GO:0072520	seminiferous tubule development	IMP	J:104620
Biological Process	GO:0060009	Sertoli cell development	IMP	J:104620
Biological Process	GO:0007530	sex determination	ISO	J:164563
Biological Process	GO:0007530	sex determination	IMP	J:71149
Biological Process	GO:0007338	single fertilization	IMP	J:104620
Biological Process	GO:0007283	spermatogenesis	IMP	J:104620
Biological Process	GO:0007356	thorax and anterior abdomen determination	IMP	J:14317
Biological Process	GO:0001657	ureteric bud development	IMP	J:54493
Biological Process	GO:0001570	vasculogenesis	IMP	J:102417
Biological Process	GO:0001570	vasculogenesis	IMP	J:102417
Biological Process	GO:0001570	vasculogenesis	IMP	J:102417
Biological Process	GO:0061032	visceral serous pericardium development	ISO	J:164563
Biological Process	GO:0061032	visceral serous pericardium development	IMP	J:52756
Biological Process	GO:0061032	visceral serous pericardium development	TAS	J:169941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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