GO Annotations Graph

• Symbol: Xrcc1
• Name: X-ray repair complementing defective repair in Chinese hamster cells 1
• ID: MGI:99137

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity	IMP	J:125414
Molecular Function	GO:0160002	ADP-D-ribose modification-dependent protein binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0032356	oxidized DNA binding	ISO	J:164563
Molecular Function	GO:0072572	poly-ADP-D-ribose binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:125414
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	IDA	J:125414
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Biological Process	GO:0006284	base-excision repair	ISO	J:164563
Biological Process	GO:0006284	base-excision repair	ISO	J:155856
Biological Process	GO:0006284	base-excision repair	IBA	J:265628
Biological Process	GO:0021587	cerebellum morphogenesis	IMP	J:241443
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IMP	J:152528
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	IMP	J:125414
Biological Process	GO:0021766	hippocampus development	IMP	J:152528
Biological Process	GO:1905765	negative regulation of protection from non-homologous end joining at telomere	IMP	J:125414
Biological Process	GO:0010836	negative regulation of protein ADP-ribosylation	ISO	J:164563
Biological Process	GO:0010836	negative regulation of protein ADP-ribosylation	IMP	J:241443
Biological Process	GO:1904877	positive regulation of DNA ligase activity	ISO	J:164563
Biological Process	GO:1903518	positive regulation of single strand break repair	IGI	J:241443
Biological Process	GO:1903518	positive regulation of single strand break repair	ISO	J:164563
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	ISO	J:164563
Biological Process	GO:0033194	response to hydroperoxide	ISO	J:164563
Biological Process	GO:0000012	single strand break repair	IEA	J:72247
Biological Process	GO:0061819	telomeric DNA-containing double minutes formation	IMP	J:125414
Biological Process	GO:0050882	voluntary musculoskeletal movement	IGI	J:241443
Biological Process	GO:0050882	voluntary musculoskeletal movement	ISO	J:164563
Biological Process	GO:0050882	voluntary musculoskeletal movement	IMP	J:241443