GO Annotations Graph

• Symbol: Zp3
• Name: zona pellucida glycoprotein 3
• ID: MGI:99215

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0032190	acrosin binding	ISO	J:164563
Molecular Function	GO:0032190	acrosin binding	IBA	J:265628
Molecular Function	GO:0030246	carbohydrate binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:169805
Molecular Function	GO:0005515	protein binding	IPI	J:26882
Molecular Function	GO:0005515	protein binding	IPI	J:20319
Molecular Function	GO:0005515	protein binding	IPI	J:73170
Molecular Function	GO:0005515	protein binding	IPI	J:43773
Molecular Function	GO:0048018	receptor ligand activity	IMP	J:169895
Molecular Function	GO:0048018	receptor ligand activity	IDA	J:169811
Molecular Function	GO:0035804	structural constituent of egg coat	IMP	J:86870
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:75669
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:169986
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0035805	egg coat	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:86870
Cellular Component	GO:0005886	plasma membrane	IDA	J:169805
Cellular Component	GO:0005886	plasma membrane	IDA	J:169986
Biological Process	GO:0007339	binding of sperm to zona pellucida	IMP	J:169805
Biological Process	GO:0007339	binding of sperm to zona pellucida	IGI	J:77459
Biological Process	GO:0007339	binding of sperm to zona pellucida	ISO	J:164563
Biological Process	GO:0007339	binding of sperm to zona pellucida	IBA	J:265628
Biological Process	GO:0007339	binding of sperm to zona pellucida	IPI	J:43773
Biological Process	GO:0007339	binding of sperm to zona pellucida	IDA	J:73170
Biological Process	GO:0001825	blastocyst formation	IMP	J:170041
Biological Process	GO:0035803	egg coat formation	IMP	J:169882
Biological Process	GO:0035803	egg coat formation	IMP	J:86870
Biological Process	GO:0035803	egg coat formation	IBA	J:265628
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	IDA	J:170041
Biological Process	GO:2000360	negative regulation of binding of sperm to zona pellucida	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:169876
Biological Process	GO:0048599	oocyte development	IMP	J:169882
Biological Process	GO:2000368	positive regulation of acrosomal vesicle exocytosis	ISO	J:164563
Biological Process	GO:2000344	positive regulation of acrosome reaction	ISO	J:164563
Biological Process	GO:2000344	positive regulation of acrosome reaction	IDA	J:169811
Biological Process	GO:2000344	positive regulation of acrosome reaction	IBA	J:265628
Biological Process	GO:2000388	positive regulation of antral ovarian follicle growth	IMP	J:169882
Biological Process	GO:2000388	positive regulation of antral ovarian follicle growth	IMP	J:170041
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:169876
Biological Process	GO:0002922	positive regulation of humoral immune response	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	IDA	J:169876
Biological Process	GO:0032753	positive regulation of interleukin-4 production	IDA	J:169908
Biological Process	GO:0002687	positive regulation of leukocyte migration	IDA	J:169876
Biological Process	GO:2000386	positive regulation of ovarian follicle development	IDA	J:169876
Biological Process	GO:2000386	positive regulation of ovarian follicle development	IMP	J:169908
Biological Process	GO:0042102	positive regulation of T cell proliferation	IDA	J:169908
Biological Process	GO:0032729	positive regulation of type II interferon production	IDA	J:169908
Biological Process	GO:0001809	positive regulation of type IV hypersensitivity	IDA	J:169908
Biological Process	GO:0010469	regulation of signaling receptor activity	IMP	J:169895
Biological Process	GO:0010469	regulation of signaling receptor activity	IDA	J:169811