GO Annotations Graph

• Symbol: Arf6
• Name: ARF GTPase 6
• ID: MGI:99435

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	TAS	J:171185
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	TAS	J:42235
Molecular Function	GO:0003924	GTPase activity	TAS	J:171185
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:184675
Molecular Function	GO:0005515	protein binding	IPI	J:161308
Molecular Function	GO:0005515	protein binding	IPI	J:207374
Molecular Function	GO:0005515	protein binding	IPI	J:188708
Molecular Function	GO:0031996	thioesterase binding	ISO	J:164563
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:42235
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0030139	endocytic vesicle	IBA	J:265628
Cellular Component	GO:0005768	endosome	IDA	J:171185
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	TAS	J:42235
Cellular Component	GO:0031527	filopodium membrane	ISO	J:164563
Cellular Component	GO:0090543	Flemming body	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:42235
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:164563
Cellular Component	GO:0055038	recycling endosome membrane	IBA	J:265628
Cellular Component	GO:0001726	ruffle	ISO	J:155856
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:155856
Biological Process	GO:0030866	cortical actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0032456	endocytic recycling	ISO	J:164563
Biological Process	GO:0032456	endocytic recycling	ISO	J:155856
Biological Process	GO:1902217	erythrocyte apoptotic process	IMP	J:111404
Biological Process	GO:0090162	establishment of epithelial cell polarity	IMP	J:156525
Biological Process	GO:0097284	hepatocyte apoptotic process	IMP	J:111404
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0001889	liver development	IMP	J:111404
Biological Process	GO:0099562	maintenance of postsynaptic density structure	ISO	J:155856
Biological Process	GO:2000171	negative regulation of dendrite development	ISO	J:155856
Biological Process	GO:2000009	negative regulation of protein localization to cell surface	IDA	J:257317
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0120183	positive regulation of focal adhesion disassembly	IMP	J:263382
Biological Process	GO:0051549	positive regulation of keratinocyte migration	IMP	J:263382
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IDA	J:171185
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:164563
Biological Process	GO:0034394	protein localization to cell surface	IDA	J:171185
Biological Process	GO:0036010	protein localization to endosome	ISO	J:164563
Biological Process	GO:0036010	protein localization to endosome	IMP	J:201931
Biological Process	GO:0015031	protein transport	TAS	J:42235
Biological Process	GO:0060998	regulation of dendritic spine development	IMP	J:168205
Biological Process	GO:0060998	regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:0051489	regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0010975	regulation of neuron projection development	IMP	J:245108
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:155856
Biological Process	GO:0035020	regulation of Rac protein signal transduction	ISO	J:164563
Biological Process	GO:0034143	regulation of toll-like receptor 4 signaling pathway	NAS	J:171185
Biological Process	GO:0097178	ruffle assembly	ISO	J:164563
Biological Process	GO:0048488	synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0016192	vesicle-mediated transport	IBA	J:265628