GO Annotations Graph

• Symbol: Nr3c2
• Name: nuclear receptor subfamily 3, group C, member 2
• ID: MGI:99459

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0034056	estrogen response element binding	IBA	J:265628
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003707	nuclear steroid receptor activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:75791
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0005496	steroid binding	ISO	J:155856
Molecular Function	GO:0005496	steroid binding	IDA	J:75791
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0098982	GABA-ergic synapse	EXP	J:137143
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:137143
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:137143
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:137143
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0038166	angiotensin-activated signaling pathway	IMP	J:206174
Biological Process	GO:1904045	cellular response to aldosterone	ISO	J:155856
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IMP	J:77285
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0055075	potassium ion homeostasis	IMP	J:206174
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:137143
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:137143
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:137143
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:137143
Biological Process	GO:0002017	regulation of blood volume by renal aldosterone	IMP	J:206174
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IDA	J:137143
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	EXP	J:137143
Biological Process	GO:1904451	regulation of potassium:proton exchanging ATPase activity	IDA	J:206174
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0035812	renal sodium excretion	IMP	J:77285
Biological Process	GO:0007165	signal transduction	IMP	J:206174