Notch3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Notch3
notch 3
MGI:99460

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	IPI	J:183220
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:58381
Molecular Function	GO:0005515	protein binding	IPI	J:225486
Molecular Function	GO:0005515	protein binding	IPI	J:225486
Molecular Function	GO:0005515	protein binding	IPI	J:40289
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9017868
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9016915
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9017420
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-9013647
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-9013660
Cellular Component	GO:0005634	nucleus	IDA	J:225486
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IC	J:58381
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9012873
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9012893
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9013059
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:114702
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0048844	artery morphogenesis	IMP	J:216917
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:72247
Biological Process	GO:0030900	forebrain development	IGI	J:101735
Biological Process	GO:0072104	glomerular capillary formation	IEP	J:97734
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:96080
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:96080
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:216917
Biological Process	GO:0014016	neuroblast differentiation	IMP	J:96080
Biological Process	GO:0030182	neuron differentiation	IMP	J:96080
Biological Process	GO:0048663	neuron fate commitment	IGI	J:101735
Biological Process	GO:0007219	Notch signaling pathway	IC	J:58381
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:154293
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:155856
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IDA	J:154293
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:216917
Biological Process	GO:0050793	regulation of developmental process	IEA	J:72247
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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