GO Annotations Graph

• Symbol: Sct
• Name: secretin
• ID: MGI:99466

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046659	digestive hormone activity	ISO	J:155856
Molecular Function	GO:0001664	G protein-coupled receptor binding	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0021542	dentate gyrus development	IMP	J:169029
Biological Process	GO:0002024	diet induced thermogenesis	IDA	J:281249
Biological Process	GO:0021766	hippocampus development	IMP	J:140787
Biological Process	GO:0009992	intracellular water homeostasis	ISO	J:155856
Biological Process	GO:1903640	negative regulation of gastrin-induced gastric acid secretion	ISO	J:155856
Biological Process	GO:1903640	negative regulation of gastrin-induced gastric acid secretion	IBA	J:265628
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:169029
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:169029
Biological Process	GO:0097150	neuronal stem cell population maintenance	IMP	J:169029
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0050996	positive regulation of lipid catabolic process	IMP	J:208291
Biological Process	GO:0050996	positive regulation of lipid catabolic process	IDA	J:281249
Biological Process	GO:0090187	positive regulation of pancreatic juice secretion	ISO	J:155856
Biological Process	GO:0090187	positive regulation of pancreatic juice secretion	IBA	J:265628
Biological Process	GO:0090274	positive regulation of somatostatin secretion	ISO	J:155856
Biological Process	GO:0090274	positive regulation of somatostatin secretion	IBA	J:265628
Biological Process	GO:0032098	regulation of appetite	IDA	J:281249
Biological Process	GO:0032098	regulation of appetite	IMP	J:273530
Biological Process	GO:0048167	regulation of synaptic plasticity	IMP	J:140787
Biological Process	GO:0031667	response to nutrient levels	IDA	J:281249
Biological Process	GO:0008542	visual learning	IMP	J:169029